Prakash R, Miller CC III, Suki WN
Anticardiolipin antibody in patients on maintenance
hemodialysis and its association with recurrent arteriovenous graft
Am J Kidney Dis
(Aug) 26:347-352 1995
In a 30 month retrospective analysis of 91 patients on chronic hemodialysis
for at least six months, 22% of those with arteriovenous grafts (AVG) and 6%
with arteriovenous fistulas (AVF) had IgG anticardiolipin antibodies. For
with AVG the odds ratio of having had 2 or more thromboses was 3.7 (95% C.I.
1.2 to 11.8; p< 0.04). Anticardiolipin antibody was not associated with
thromboses in those with AVF.
A prospective study is now required to determine whether the presence of
anticardiolipin antibody is causally related to thromboses. It will also be
important to ascertain whether AVG actually elicit the development of
anticardiolipin antibodies or whether antibodies were seen in patients with
because of selection bias.
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Basic hemodialysis :
Vascular Access: graft/fistula