Summerson JH, Bell RA, Konen JC
Racial differences in the prevalence of microalbuminuria
Am J Kidney Dis
(Oct) 26:577-579 1995
The presence of microalbuminuria predicts the development of diabetic
nephropathy and is an independent predictor of cardiac mortality in patients
hypertension, although a relationship between microalbuminuria and
nephropathy in hypertension is not clear. African-American patients are 6-
more likely to develop hypertensive renal failure than are white patients.
this study, urinary albumin excretion rate (timed overnight sample) was
measured in 109 patients (38 A-A; 71 white) with essential hypertension
clinical proteinuria. 32% of A-A but only 14% of white patients had
microalbuminuria (urine albumin excretion more than 30 ug/min). There were
no racial differences in
glyHb, serum creatinine, duration or type of BP Rx; only race and systolic BP
had significant independent associations with UAE. Microalbuminuria may be
more prevalent in A-A hypertensive patients and may be a marker for
susceptibility to nephropathy.
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Kidney in hypertension