HDCN Article Review/Hyperlink

Stricker RB et al

Pancreatorenal syndrome associated with combination antiretroviral therapy in HIV infection

Lancet (Jun) 349:1745-1746 1997

The authors describe two patients with HIV who were treated with a combination aof a nucleoside analogue and protease inhibitor who developed acute pancreatitis and acute renal failure. Symptoms resolved with supportive treatment, and recurred with reinstitution of combination therapy. Causality remains to be proven, but this potential association needs to be kept in mind. (John T. Daugirdas, M.D., University of Illinois at Chicago)