HDCN Article Review/Hyperlink

Lindsay R, Nieves J, Formica C, Henneman E, et al

Randomised controlled study of the effect of parathyroid hormone on vertebral-bone mass and fracture incidence among postmenopausal women on oestrogen with osteoporosis

Kidney Int (Aug) 52:550-555 1997

We tend to think of PTH as the "evil hormone" of renal osteodystropy, because of its osteoclastic properties. With adynamic bone disease, we also are forced to recall the osteoblastic actions of this hormone. In this paper in non-ESRD patients, 1 -34 PTH given daily subQ to postmenopausal women was shown to have a marked salutary effect on both bone density and fracture rate.

The abstract of this paper is available from the National Library of Medicine's PubMed site: click here .