HDCN Article Review/Hyperlink

Fleming MD, Trenor CC 3rd, Su MA, Foernzler D, Beier DR, Dietrich WF, Andrews NC

Microcytic anemia mice have a mutation in Nramp2, a candidate iron transporter gene

Nat Gen (Aug) 16:383-386 1997

This paper reports the discovery (in mice) of the protein that transports iron into the body, and which may lead to a better understanding of iron deficiency anemia and hemochromatosis.

The abstract is available from the National Library of Medicine's PubMed site: click here .

A related paper in Nature demonstrating cloning and characterization of the intestinal iron transporter in mammals by Gunshin et al. is also of interest.