HDCN Article Review/Hyperlink

Staessen JA, Fagard R, Thijs L, Celis H, Arabidze GG et al

Randomized double-blind comparison of placebo and active treatment for older patients with isolated systolic hypertension. The Syst-Eur Trial

Lancet (Sep) 350:757-764 1997

This paper presents the first definitive evidence that a calcium channel blocker (nitrendipine) can improve a hard cardiovascular endpoint! The abstract of this paper is available from the National Library of Medicine's PubMed site: click here .