The Helicobacter pylori genome -- new insights into
pathogenesis and therapeutics
N Engl J Med
(Mar) 338:832-833 1998
This editorial is available from the NEJM:
What does this have to do with nephrology? Many of our patients can't take
oral iron. This
editorial describes specific proteins in H. pylori that are
highly conserved that
target iron avidity. Perhaps our dialysis patients who are intolerant of
iron are infected with
this organism, and perhaps tolerance to oral iron therapy might be mitigated
by eradicative therapy.
Just a hypothesis...
(John T. Daugirdas, M.D., University of Illinois at Chicago)