Clement DL, De Buyzere M, Missault L, for the OvA investigators
Values of 1,2,3 hour segments or ambulatory blood pressure pattern in essential hypertension
12th Annual ASH Meeting
Am J Hypertens (Apr) 10:61A 1997

The use of ambulatory blood pressure monitoring is hampered by the lack of trials showing that the information provided is superior to clinic blood pressure. Preliminary evidence suggests that the average blood pressure obtained may be superior to office blood pressure measurement. Furthermore some aspects of the blood pressure profile (sleep blood pressure) are only obtainable through ambulatory monitoring. The study abstract here examines whether shorter periods of study may predict the average daytime blood pressure.

The authors performed ambulatory blood pressure monitoring as a substudy in the Office versus Ambulatory (OvA) BP study which is examining the relative abilities of these two methods to predict clinical outcome. The authors compared 1, 2, and 3 hour averages to whole day (12 hour) averages of blood pressure in 1981 patients enrolled. They also studied the correlation of these averages with left ventricular mass. They found that all three shorter periods were highly correlated with 12 hour averages and also that the correlation coefficients with left ventricular mass were similar irrespective of which average period was used.

Comment: These data do indeed suggest that shorter periods of ambulatory monitoring study may substitute in certain situations for a full 12 or 24 hour study. This shortened study would reduce cost and improve patient tolerability. However, such short studies will not readily identify the effects of drug therapy and can offer no information on sleep blood pressure. The 6 hour daytime study has previously been suggested to identify patient with white-coat hypertension. (George Mansoor, M.D., University of Connecticut)

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12th Annual ASH Meeting
H: Exam and lab tests : Ambulatory monitoring