Levin NW, Stannard DC, Gotch F, Port FK
Comparison of mortality risk by Kt/V single pool vs. double pool analysis in diabetic and non-diabetic dialysis patients
Am Soc Nephrol
J Am Soc Nephrol (abstract) (Nov) 6:606 1995

This is a reanalysis of the USRDS Case Mix Adequacy Data set focusing on the relation between delivered therapy and mortality. Whereas in previous analyses the single-pool Kt/V was examined, in this paper the equilibrated or double-pool Kt/V (derived from the single-pool Kt/V and dialysis session length using the Daugirdas-Schneditz rate equation) was used. Overall there appeared to be little benefit regarding survival at double-pool Kt/V values greater than 1.0. However, there was a trend in diabetic patients for a survival benefit up to double-pool Kt/V values of 1.2 (not statistically significant).

Comment: These data suggest that increasing double-pool Kt/V much above 1.0-1.2 may not be of much benefit to patients undergoing 3x/week hemodialysis. (Daugirdas)

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Am Soc Nephrol
CRF: Problem Areas : Outcomes (Morbidity, Mortality)
Basic hemodialysis : Adequacy, prescription, urea kinetics