Rahman M, Austen A, Brown R, Phinney M, Carey J, Kalayjian R, Weigel K, Smith MC
Prednisone ameliorates the progression on HIV-associated nephropathy
Am Soc Nephrol
J Am Soc Nephrol (abstract) (Nov) 6:430 1995

This is a follow-up to a previous recently published report by this group in JASN in 1994 suggesting that prednisone may be of benefit to patients with HIV-associated nephropathy. 19 patients with clinical or biopsy-proven HIV-associated nephropathy were treated with prednisone at a dose of 60 mg per day for 2-6 weeks and followed for a median of 56 weeks. 17 patients responded with a fall in serum creatinine from an average of 8 mg/dL to 3 mg/dL, and a fall in urinary protein excretion from 9 to 3 g/24 hours. Four patients were able to discontinue dialysis. Five patients relapsed when prednisone was discontinued but improved with a second course of steroid treatment. The authors conclude that prednisone therapy delays or prevents the development of ESRD in HIV nephropathy, although 40% ultimately progressed to end stage renal failure. (Daugirdas)

To go back use the BACK button on your browser.
Otherwise click on the desired link to this article below:
Am Soc Nephrol
Proteinuria/Hematuria : HIV-associated nephropathy