Rao TKS, Friedman EA
Decreasing incidence of severe acute renal failure in patients with HIV infection
Am Soc Nephrol
J Am Soc Nephrol (abstract) (Nov) 6:474 1995

The yearly incidence of severe acute renal failure (creatinine >6) in HIV positive and non-HIV positive patients were compared for hospital admissions to Kings County Hospital Center in Brooklyn, NY from 1984 through 1993. The overall rate of ARF dropped in the HIV positive patients (2% of admissions 1986-1989, 1% of admissions 1990-1993), while it stayed the same for non-HIV positive patients (0.2% of hospital admissions during the same two time periods). The authors conclude that the incidence of ARF is dropping in HIV positive patients, and speculate that this is due to greater use of antiretroviral agents, greater awareness of the potential nephrotoxicity of drugs used to treat HIV patients, more widespread use of prophylaxis against opportunistic infections and better general care overall of HIV patients. These speculations are unproved but seem plausible. (Pastan)

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Am Soc Nephrol
Proteinuria/Hematuria : HIV-associated nephropathy
ARF etiology : ARF: etiology, general