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Sodium Profiling: The Key to Reducing Symptoms of Dialysis?
(Vol 34/No. 4. On-line test expires: 08/20/2009)
To receive continuing education credit, you must read the information in this article and take an on-line post test and fill out an on-line program evaluation form. The certificate will then be generated for you as a .pdf file which you can print out locally on your computer.

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  AUTHOR
Paula McLaren, PgDipHigherEd, BSc (Hons),RGN
Paula McLaren, PgDipHigherEd, BSc (Hons), RGN, is Principal Lecturer, The University of Hertfordshire, Hatfield, Hertfordshire, United Kingdom. For more information on this article, contact the author at P.McLaren@herts.ac.uk.
Cheri Hunter, MSc, BA (Hons) Ed, Cert Ed (Distinction), Cert Counselling, FETC, RGN, Dip Nursing (Canada)
Cheri Hunter, MSc, BA (Hons) Ed, Cert Ed (Distinction), Cert Counselling, FETC, RGN, Dip Nursing (Canada), is Associate Dean, University of Hertfordshire, Bedfordshire and Hertfordshire Postgraduate Medicine, Hatfield, Hertfordshire, United Kingdom.
  OUTLINE

Background/Aims: A systematic review was undertaken in order to critically appraise the current knowledge base of sodium profiling in hemodialysis. Between 15%-80% of patients on hemodialysis experience symptoms of dialysis intolerance every dialysis session. The purpose of this review was to identify whether sodium profiling is an effective intervention in removing or reducing these untoward effects.
Methods: A literature search was undertaken using Medline and Embase. Inclusion criteria were primary research or controlled clinical trials published between January 1990 and June 2006 and studies in the chronic dialysis setting and studies that identified sodium profiling as the intervention in hemodialysis or hemodiafiltration. Articles excluded included: those that could not establish whether sodium profiling was the intervention responsible for the outcome; articles on hemofiltration; and review articles and research pertaining to the acute setting. Thirteen articles met the inclusion criteria and were included in the final review.
Results: A number of flaws were identified with methodological adequacy and consistency of findings. It was not possible to determine whether positive effects outweighed negative effects in this review. In the majority of studies, there was a lack of follow-up and the inability to determine long-term outcomes of patients who received sodium profiling.
Conclusion: This evaluative review could not provide evidence to support the clinical use of sodium profiling in the population of patients on hemodialysis who are symptomatic . There remains a theoretical base for the use of sodium profiling, however further studies are needed providing consistency in methodology, looking not only at reduction in morbidity but effects on quality of life, long-term outcomes, and mortality.

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  CE RELATED INFORMATION
This offering for 1.5 contact hours is being provided by the American Nephrology Nurses’ Association (ANNA), which is accredited as a provider and approver of continuing education in nursing by the American Nurses’ Credentialing Center-Commission on Accreditation (ANCCCOA). This educational activity is approved by most states and specialty organizations that recognize the ANCC-COA accreditation process. ANNA is an approved provider of continuing education in nursing by the California Board of Registered Nursing, BRN Provider No. 00910; and the Kansas State Board of Nursing, Provider No. LT0148-0738. This offering is accepted for RN and LPN relicensure in Kansas

  EDUCATIONAL OBJECTIVES

Goal:
To provide information about sodium profiling in hemodialysis.

Objectives:
1. Describe the possible role sodium plays in dialysis intolerance.
2. Explain the reasons sodium profiling is thought to be useful in avoiding dialysis intolerance.
3. Analyze the methods, results, and conclusions provided from a literature review study on sodium profiling.

AUTHOR DISCLOSURE STATEMENT
Paula McLaren has no conflicts of interest to disclose.
Cheri Hunter has no conflicts of interest to disclose.

 ANNA and HDCN CE POLICY STATEMENTS

The CE policy and disclosure statements of the American Nephrology Nurses' Association are given in detail on the Symposium Home Page. The CE policy statements of HDCN are listed on this page.