Kasiske  
Weisinger  

New Insights into Common Problems After Kidney Transplantation
Bertram L. Kasiske, MD and Jose R. Weisinger, MD
(ASN Renal Week Clinical Nephrology Conference, November, 2007.)
Kasiske: Which forms of cancer are increased after renal transplantation, and what explanations account for these increases? Are there any particular immunosuppressive regimens associated with a higher or lower incidence of cancer? If so, which ones? Weisinger: What characterizes post-transplant bone disease? What happens typically to parathyroid hormone? To serum phosphorus? Should the hypophosphatemia be treated? How are phosphatonins involved? What do we know from bone biopsy studies? What are reasonable short and long term strategies to minimize bone loss after transplantation? What evidence will KDIGO be reviewing in this area? (more...)


Updated: February 03, 2010 (Feb03)
Feb03 NEJM: Many people in a coma are not really in a coma - willful modulation of brain activity.
Dec31 Officials re-examining organ donor rules after transmittal of amoebic brain infection
Dec29 Transplanted organs from donor who died of undiagnosed brain disease transmitted amoebic brain infection to recipient.
Dec22 Deoxycytidine kinase enzyme shown to profoundly affect adaptive immune system.
Dec21 Facebook post brings Iowa man a new kidney.
Dec15 Kidney Care Partners letter to senators regarding immunosuppressive drug reimbursement issues.
Dec15 Reducing dialysis reimbursement to pay for transplant drugs draws opposition.
Dec14 Scientists isolate new antifreeze molecule from beetle.
Dec11 Blood stem cell transplants "cure" sickle cell disease in 9/10 adults
Dec09 Australia lifts ban on xenotransplantation.
Dec08 FDA panel recommends approval of everolimus for transplant rejection with a risk mitigation plan.
Dec08 West Nile virus infection may persist in the kidneys for years after infection.
Dec07 Donor kidneys from which renal masses have been removed yield good results.
Dec04 Observational study suggests remarkable protection against graft-versus-host disease by statins.
Dec03 Novel "locked nucleic acid" drug markedly lowers hepatitis C viral counts in chimpanzees.
Industry Advances Emphasis
archive
Post Transplant Surveillance of MICA and HLA Antibodies: Impact on Graft Function (F. Reed) ASN Renal Week 2008
Management of the Patient with Skin Cancer (A. Harwood) ASN Renal Week 2008
Has Patient Survival Matched Improved Renal Survival: Short Term/Long Term? (B. Appel) ASN Renal Week 2008
Kidney Transplantation in the Elderly: Are We Avoiding Our Responsibility? (L. Friedman) ASN Renal Week 2008
Immunosuppression Management in the Patient with Cancer (L. Kasiske) ASN Renal Week 2008
What is the Effect of Proteinuria on Pharmacokinetics of Immunosuppressants? (S. Joy,) ASN Renal Week 2008
Treatment of Early and Late Antibody-Mediated Rejection (D. Pescovitz) ASN Renal Week 2008
Transplant and CKD patients at the same stage of renal insufficiency: how are they the same or different? (Kupin) RRI 2008
Viral Hepatitis in Kidney Transplantation (Martin) ASN Renal Week 2007
Recipient Evaluation (J. Cohen) ASN Renal Week 2007
Nagging Problems after Transplant: Hair Loss, Diarrhea, Gingival Hyperplasia, Muscle Weakness, Recurrent FSGS (B. Adey,) ASN Renal Week 2007
Cardiovascular Disease and Anemia in the Transplant Patient (Djamali) ASN Renal Week 2007
New Insights into Common Problems After Kidney Transplantation (Kasiske, Weisinger) ASN Renal Week 2007
Organ Allocation Within the USA (W. Williams) ASN Renal Week 2007
Timelines: Overview of Management (J. Tomlanovich) ASN Renal Week 2007
Therapy for Antibody Mediated Rejection (M. Gloor) ASN Renal Week 2007
Living Donor Evaluation (L. Davis) ASN Renal Week 2007
Post Transplant Diabetes Mellitus (G. Cosio) ASN Renal Week 2007
Prostate Cancer and Transplant (V. Meng) ASN Renal Week 2007
Options for the Sensitized Patient (C. Jordan) ASN Renal Week 2007
Transplanting the High Risk Patient (J. Cohen) ASN Renal Week 2007
Recurrent Disease in the Allograft (Hariharan) ASN Renal Week 2007
Pregnancy after Transplant: Newer Immunosuppressive Agents and the Outcome of Pregnancy and the Offspring (B. McKay) ASN Renal Week 2007
Renal Dysfunction in Non-Renal Transplants (O. Ojo) ASN Renal Week 2007
Pathology of Chronic Allograft Nephropathy (S. Randhawa) ASN Renal Week 2007
New Factors Associated with Transplant Loss (B. Mannon) ASN Renal Week 2007
Post Transplant Malignancies (B. Mannon) ASN Renal Week 2007
Getting Your Patient a Transplant: Working the Allocation System (B. Leichtman) ASN Renal Week 2007
Immunosuppression Trends in Transplantation (S. Gaston) ASN Renal Week 2007
Post Transplant Bone Disease (A. Josephson) ASN Renal Week 2007
The Pathology of Acute Allograft Dysfunction (C. Nast) ASN Renal Week 2007
Expediting the Transplant Evaluation: Nuts and Bolts (B. Mannon) ASN Renal Week 2007
Transplantation ( E. Hricik) ASN Renal Week 2007
Transplanting the Non-Adherent Patient: Where Are We Now? (Chapman) ASN Renal Week 2007
Immunological Assessment of the Transplant Patient (J. Norman) ASN Renal Week 2007
Management of Chronic Allograft Nephropathy (Chapman) ASN Renal Week 2007
How the Immune System Recognizes an Allograft? (D. Samaniego-Picota) ASN Renal Week 2007
Disparities in Access to Transplantation and Outcomes (S. Gaston) ASN Renal Week 2007
Quality of Care in the Transplant Population (L. Kasiske) ASN Renal Week 2007
Options for the Diabetic Renal Transplant Recipient (Pavlakis) ASN Renal Week 2007
What's New in Transplant Immunology? (Wood) ASN Renal Week 2007
Pregnancy in the Transplant Recipient (B. McKay) ASN Renal Week 2007
Transplantation ( E. Hricik) ASN Renal Week 2007
Do We Need Calcineurin-Inhibitors and/or Steroids? (W. Steiner) ASN Renal Week 2007
Post Transplant Infections (C. Brennan) ASN Renal Week 2007
Renal Transplantation (Torres) ASN Renal Week 2007
ASTS 7th Annual Winter Symposium ASTS; 01-07
Emphasizing kidney donation: the long-term outcome of living donors (X. Garg) RRI 2007
Transplantation: Medical and Immunosuppressive Management ASN Board Review 2006
The Spectrum of Sensitization Before and After Transplantation: Management Issues (Tinckam, Akalin, Watschinger, Jordan) ASN Renal Week 2005 (audiofiles)
State-of-the-Art Lecture : Tipping the Immune Balance Toward Tolerance (Strom) ASN Renal Week 2005 (audiofiles)
Transplantation: Key Issues for the General Nephrologist (Murphy, Rigatto, Mannon) ASN Renal Week 2005
Post-Transplant Infections: Updating the General Nephrologist (Rubin, Pescovitz, Ramos) ASN Renal Week 2005
Transplantation: What the General Nephrologist Must Know (Parts 3 and 4) (Heeger, Hricik, Danovitch, Chapman, Bunnapradist, Gabardi; Akalin, Chandraker, Martin, Cohen, Thomas) ASN Renal Week 2005 (audiofiles)
Transplantation: What the General Nephrologist Must Know (Parts 1 and 2) (Norman, Tinckam, Danovitch, Chandraker, Nast, Davis; Kasiske, Pavlakis, Brennan, Josephson, Davis) ASN Renal Week 2005 (audiofiles)
Highlights from the 2005 American Transplant Congress: Renal Transplantation (Gallon, Vanrenterghem, Mannon) ASN Renal Week 2005 (audiofiles)
New Immunosuppressive Agents in Renal Transplantation (Steinberg, Grinyo, Knechtle) ASN Renal Week 2005 (audiofiles)
Managing the Transplant Patient: What the General Nephrologist Needs to Know (Helderman, Blumberg, Kasiske, Abbott) ASN Renal Week 2005 (audiofiles)
State-of-the-Art Lecture : Tipping the Immune Balance Toward Tolerance (Strom) ASN Renal Week 2005 (audiofiles)
The High Risk Transplant Patient (Kiberd, Wali, Adey, Chapman, Chandraker) ASN Renal Week 2005 (audiofiles)
CMV infection and management (Brennan) ASN Renal Week
Infections and Renal Complications of Immunosuppression: An Update (Roth) ASN 2004
New Infectious Timeline (Davis) ASN 2004
Infectious Diseases After Immunosuppression in the Non-Transplant Kidney Patient Population (Brennan) ASN 2004
Immunosuppression: Induction and Maintenance (Vincenti) ASN 2004
Chronic Allograft Nephropathy and Recurrent Disease (Nankivell) ASN 2004
B Cell and the Humoral Alloimmune Response (Denton) ASN 2004
Donor / Recipient Evaluation (Davis) ASN 2004
Post-transplant diabetes mellitus (Weir) ASN Renal Week
Evaluation and management of the hepatitis C virus infected pretransplant candidate (Roth) ASN Renal Week
Hepatitis and the renal transplant recipient (Pereira) ASN Renal Week
New viral infection: HHV-6, west nile virus (Limaye) ASN Renal Week
Polyoma virus (Hirsch) ASN Renal Week

American Transplant Congress -- Oral abstracts Am J Transplant (May 2009)
Uremic cardiac hypertrophy is reversed by rapamycin but not by lowering of blood pressure (Siedlecki) Kidney Int (Apr 2009)
Primum non nocere: is chronic kidney disease staging appropriate in living kidney transplant donors? Am J Transplant (Apr 2009)
Platelets influence vascularized organ transplants from start to finish Am J Transplant (Jan 2008)
Transplant center regulations: ASTS vs. CMS Am J Transplant (Dec 2008)
Managing cancer risk and decision making after kidney transplantation Am J Transplant (Nov 2008)
What's next in the (drug) pipeline (for transplantation) Am J Transplant (Oct 2008)
Pharmacogenetics of immunosuppressants: progress, pitfalls and promises (Cattaneo D et al) Am J Transplant - Jul - 08
Atherosclerotic renal artery stenosis: overtreated but underrated? J Am Soc Nephrol (Apr 2008)
Trends in organ donation and transplantation in the United States, 1997-2006 Am J Transplant (Apr 2008)
Transplant glomerulopathy Am J Transplant (Mar 2008)
A randomized, multicenter study of steroid avoidance, early steroid withdrawal or standard steroid therapy in kidney transplant recipients Am J Transplant (Feb 2008)
Rapid remission of steroid and mycophenolate mofetil-resistant minimal change nephrotic syndrome after rituximab therapy Nephrol Dial Transplant (Jan 2008)
Alemtuzumab (Campath-1H) in kidney transplantation Am J Transplant (Jan 2008)
Renal transplantation in the ANCA-associated vasculitides (Geetha et al) Am J Transplant (Dec 2007)
Evaluation of adult kidney transplant candidates (Bunnapradist et al) Am J Kidney Dis (Nov 2007)
Immunosuppression minimization in pediatric transplantation (Sarwal et al) Am J Transplant (Oct 2007)
Organ donation after cardiac death (Steinbrook) N Engl J Med (Jul 2007)
Checklist: Passport, plane ticket, organ transplant (Bramstedt et al) Am J Transplant (Jul 2007)
Conditional gene expression: a new tool for the transplantologist Am J Transplant 04-07
Report of the First World Transplant Congress (Cravdei et al) CJASN (03-2007)
Report of the First World Transplant Congress CJASN 03-07
The interleukin-12 family: new players in transplantation immunity? Am J Transplant 02-07
The interleukin-12 family: new players in transplantation immunity? (Goriely, Goldman) Am J Transplant (02-2007)
Gal knockout and beyond (Zhong) Am J Transplant 01-07
Gal knockout and beyond (Zhong) Am J Transplant (01-2007)
Pathogenesis and prevention of bone loss in patients who have kidney disease and receive long-term immunosuppression JASN (01-2007)
Recurrent glomerulonephritis after kidney transplantation (Choy, Chan, Lai) Am J Transplant 11-06
Emerging issues in hepatitis C virus-positive liver and kidney transplant recipients (Bloom and Lake). Am J Transplant 10-06
Developments in clinical islet, liver thoracic, kidney and pancreas transplantation in the last 5 years (Feng et al) Am J Transplant 07-06
Societies
Am Soc Transplantation
Am Soc Transplant Surgeons
NAPRTCS
Renal Pathology Society
UNOS
NKF Transplantation
Main
U.S. Transplant Reports
CTS: List of links
UNOS Calendar
Upcoming AST meetings
Topic Pages
Transplantation
Cyclosporine and the kidney
Hypertension in Tx Patients
Research
Clinical Trials.gov
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Walter Reed Army Medical Center

Dr. Kevin C. Abbott, LTC, MC
Director, Dialysis, Nephrology Service
Chief, Research and Development, Telemedicine, Walter Reed Army Medical Center, Washington, DC