American Airlines offers special fares for Nephrology course participants traveling during

February 1 - February 9, 1999: 5% off AAnytime and American Eagle round-trip domestic segments excluding Alaska. All tariff rules apply. From other areas, other reduced fares may be available to you. You must call the American Airlines Meeting Services Desk toll free number (800-433-1790) and refer to the Nephrology Star File No._______. Full AADVANTAGE mileage is awarded on all discounted fares. Seats are limited and special fares must be purchased 7-14 days in advance.

Hertz is the official car rental company for the Nephrology meeting. Special Discounted Rates with unlimited mileage are available not only during the meeting but up to one week before and one week after the meeting. Reservations should be made at least two weeks in advance. Call the Hertz meeting desk at 800-654-2240 or your travel agent using CV #18378 and the name and dates of our meeting. From Oklahoma, dial 800-522-3711. From Canada, dial 800-263-0600.

The University of California, San Diego School of Medicine is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to sponsor continuing medical education for physicians.

The University of California, San Diego School of Medicine designates this continuing medical education activity for credit hours in Category I of the Physician's Recognition Award of the American Medical Association and for the Certification Program of the California Medical Association.

If your registration must be canceled and a refund of your fee is desired, your fee, less $30 U.S. for administrative costs, will be refunded upon written request. No refunds will be made after February 1, 1999. Allow 6-8 weeks for refund.

Complete Conference Management Phone: (619) 299-6673

1660 Hotel Circle North, #220 Fax: (619) 299-6675

San Diego, CA 92108 Email: c-c-m@worldnet.att.net

HOTEL RESERVATION FORM ADVANCED NEPHROLOGY: NEPHROLOGY FOR THE CONSULTANT

AND CHECK DIRECTLY TO:

Coronado Island Marriott Resort

2000 Second Street

Coronado, California 92118

Phone: (619) 435-3000

Fax: (619) 435-4183

Number in Party ___________________ G Single G Double G Smoking G Non-Smoking

CONFERENCE REGISTRATION FORM ADVANCED NEPHROLOGY: NEPHROLOGY FOR THE CONSULTANT

LAST NAME ______________________________________________________________(M.D.) (Mr.) (Ms.) (Other)

G Physician in Practice $425 (US Funds) Advanced Nephrology

G Fellow/Resident $175 (US Funds) 1660 Hotel Circle North, #220

(with letter of verification) San Diego, CA 92108

G Workshop AA@ $20 (US Funds)

G Workshop AB@ $20 (US Funds)

G Workshop AA & B@ $35 (US Funds)

G TOTAL ____________

February 4-6, 1999 CORONADO, CALIFORNIA

The 18^th Annual Nephrology Postgraduate Course for the practicing nephrologist continues the tradition of providing in-depth information about selected areas of nephrology. This course has come to be recognized as a premier meeting which facilitates learning through close interaction amongst recognized experts and attendees in an informal setting. This year marks a transition from the traditional 4 half day sessions to include another half day with two optional workshops. These changes reflect the desire of a number of attendees to explore additional opportunities for hands on experience.

The first day of the course focuses on the Pre-ESRD patient. Several issues are addressed including a discussion of two controversial areas; the need and impact of early identification and referral of patients to the nephrologist and the use of structured protocols for management. While these topics are timely they also reflect the increasing recognition that this segment of the population deserves more systematic attention.

Thursday afternoon provides an opportunity to enroll in two optional workshops targeted to cover vascular access care and managed care issues. Both of these workshops are designed to allow a mix of didactic and hands-on experience. The faculty for both these workshops are recognized experts and we anticipate that the interactions will be highly rewarding.

Friday morning concentrates on management strategies in ESRD. Two areas of considerable controversy cover the ends of the spectrum of initiating and withdrawing dialysis. Both of these topics have significant impact on day to day management decisions the nephrologist must make. Friday afternoon=s session focuses on ICU nephrology, an emerging area requiring specific attention. Information about the changing nature of the critically ill patient is provided by two intensivists and the tricky balance between conservative management of pre-renal azotemia and initiating dialysis is covered. The vexing problem of renal involvement in hepatic failure is further defined. This session should provide an opportunity for nephrologists to hone their skills in the care of critically ill patients.

Saturday=s session presents a discussion of challenges the nephrologist is likely to face. Two of the topics cover problems faced by women, two others cover adrenal and lipid problems and the final one covers an emerging area of the long term consequences of transplantation. Each of the speakers will undoubtedly provide Apearls@ for handling these difficult situations. As always, we will strive to provide ample time for questions and to encourage vigorous discussion.

This year marks a transition in the running of this course from a seasoned, experienced clinician scientist to two relative novices in this area. Although it is difficult to fill Dr. Fanestil=s shoes, we hope to provide a informative and stimulating environment so that we can all learn form each other for the 18^th time! We look forward to seeing you in San Diego in Februray.

2000 Second Street

Coronado, CA 92118

Phone: (619) 435-3000

Fax: (619) 435-4183

The Coronado Island Marriott Resort, where the Course will be held this year, boasts an unrivaled location on beachfront property across the bay from San Diego. It is easily accessible; across the Coronado Bay Bridge, just ten minutes from downtown San Diego and the airport. The lovely guest rooms are oversized and there are lighted tennis courts, three outdoor swimming pools, a health club and spa on the property, along with two excellent restaurants. The village of Coronado, with its shops, galleries and restaurants, and the Coronado Golf Course are short distances from the hotel along with one of the finest beaches in California. Some of the fascinating attractions nearby in San Diego include the world famous San Diego Zoo, Sea World, Seaport Village, the Globe Theater and interesting Museums in beautiful Balboa Park.

February is tourist season in San Diego so be sure to make your reservations early. A limited number of rooms have been reserved for course participants and will be available on a first come, first serve basis. Rooms must be reserved by January 12^th. Use the reservation form in this brochure, or if you call please specify you are attending the ADVANCED NEPHROLOGY: NEPHROLOGY FOR THE CONSULTANT Course so you can receive our special course rate.

 REGISTRATION FEE

Physician In Practice $425 (US Funds)

Fellow/Resident $175 (US Funds)

(With letter of verification)

Workshops $20 each (A or B) or $35 for both (A and B)

AMA Category 1 Credit Hours

Enrollment fee covers lectures, printed syllabus, coffee breaks, (including morning sweet rolls) and lunch on Friday, February 5th

Moderator: David M. Ward, M.D.

8:00 Anemia Management Changing Concepts

8:45 Preventing and Managing Diabetic Renal Disease: The Role of the Nephrologist

9:30 Protocol Based Management for Pre-ESRD Patients

10:15 Coffee Break

10:30 Assessment of Structure and Function in Progressive Renal Disease

11:15 Early Identification and Referral of Patients with Kidney Disease: Does the Nephrologist make a difference?

12:00 Panel Discussion

12:30 Lunch on your own

1:30 - 5:45 OPTIONAL WORKSHOPS

1:30 - 3:30 WORKSHOP A: Vascular Access Care: The Multi-disciplinary Approach

This workshop is divided into three segments to cover several issues related to the care of chronic and temporary vascular access. There will be a initial lectures covering I) the issues of vascular access basics including choice of vascular access, principles of access flow, recirculation and access care and ii) radiological interventions to evaluate and maintain access patency. This will be followed by hands on demonstration of a) evaluation of chronic vascular access including the physical examination, static and dynamic pressure measurement, flow quantification and b) placement and care of temporary access (tunneled and non-tunneled). The final segment will provide a discussion on the economics of vascular access care including setting up and maintaining a database and will be followed by a questions and answer session.

Vascular Access Basics - Anatole Besarab, M.D.

Radiological Interventions to Maintain Access Patency - Karim Valji, M.D.

Diagnosing the Failing Vascular Access: the Physical Exam - Thomas W. Ziegler, M.D.

Prevention of Vascular Access Failure - Anatole Besarab, M.D.

Temporary and Long Term Central Venovenous Vascular Access - Karim Valji, M.D.

Cost Implications and Development of a Database for Access Management- Anatole Besarab, M.D.

3:30 - 3:45 Coffee Break

3:45 - 5:45 WORKSHOP B: Managed Care Nephrology

This workshop will focus on the financial considerations relevant to nephrologists. Each speaker will give a short talk on the topics listed and the final period will be composed of a panel discussion, including time for questions and answers.

1. The Economics of ESRD - Brian J. G. Pereira, M.D.

2. The Nephrologist as a Primary Care Provider - Jean L. Holley, M.D.

3. Developing a Renal Disease Management Program - B. Lee Luckenbill

4. Clinical Pathways and Case Management: The Collaborative Approach for ESRD - Steven Fishbane, M.D.

5:45 Adjourn

Moderator: Roland C. Blantz, M.D.

8:00 Chronic Metabolic Acidosis: Consequences and Management

8:45 Aging, Hypertension and the Kidney: a Pivotal Constellation

9:30 The Hypertensive Dialysis Patient

10:15 Coffee Break

10:30 Initiation of Dialysis for ESRD: The Healthy Start Initiative

11:15 Withholding and Withdrawing Dialysis

12:00 Panel Discussion

12:30 Hosted Luncheon

Moderator: Ravindra L. Mehta, M.D.

1:30 Multi Organ Failure: Pathophysiology and Management

2:00 Pre-Renal Azotemia: Current Concepts

2:30 The Changing Spectrum of ARDS: What the Nephrologist should know

3:00 Coffee Break

3:15 Therapeutic Challenges: Renal Involvement in Liver Failure

3:45 Therapeutic Interventions: Renal Replacement vs Renal Support

4:15 Panel Discussion

Roland C. Blantz, M.D.

Roger G. Spragg, M.D.

5:00 Adjourn

Moderator: Darrell D. Fanestil, M.D.

8:00 The Pregnant Patient with Renal Disease

8:45 The Long Term Management of the Renal Transplant Recipient

9:30 The Patient with an Adrenal Mass

10:30 Coffee Break

10:45 Lipid Abnormalities in Dialysis Patients: Assessment and Strategies for Control

11:15 Sleep Apnea Recognition and Management

12:00 Gynecologic and Reproductive Issues in Women on Dialysis

12:45 Panel Discussion

1:15 Adjourn

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