Handbook of Dialysis Fifth (5th) Edition
JT Daugirdas, PG Blake, TS Ing

Publication date: December 1, 2014

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We are very fortunate and honored to present this Fifth Edition of the Handbook of Dialysis to the nephrology community. It has been 7 years since the Fourth Edition; the long time interval reflects the relatively slow, incremental nature of improvements which have occurred in dialysis therapy during that time period. We continue with a strong international emphasis, referencing both KDOQI and KDIGO guidelines, and taking care to express laboratory measurements in both English and SI units.

The chapter on online hemodiafiltration, a therapy still not available in the United States, has been maintained and updated. A chapter on sorbent dialysis, present in the first two editions of the Handbook, but removed from the third and fourth editions as use of the REDY system dwindled, has been reinstated and modernized, given the anticipated imminent release of new sorbent-equipped hemodialysis machines for both in-center and home hemodialysis. The hemodialysis vascular access section, which grew from 1 to 2 chapters between the 3rd and 4th editions, now has expanded to 4 chapters, testimony to the importance of vascular access to overall hemodialysis patient care. In the peritoneal dialysis section, the access chapter was completely rewritten by a general surgeon with long experience and dedication in this area. Another completely rewritten chapter describes the growing use of acute peritoneal dialysis and "urgent start" PD. For both peritoneal dialysis and hemodialysis adequacy, fewer equations are used and instead, analogies help explain key concepts. More emphasis is placed on dialysis time, frequency, ultrafiltration rate, and other supplementary metrics of adequacy, including doing dialysis the "European way". To make room for expanded and additional chapters, a number of topics that were discussed in great detail in their own separate chapters in the Fourth Edition have been downsized and folded into other chapters; our goal was to maintain a slim, pocket-sized book that focuses on frequently encountered clinical problems. As in previous editions, we have tried to maintain the unique character of the Handbook of Dialysis, aiming for a resource that will be useful to both new and experienced nephrology care providers to help them in their difficult job of assuring the best treatment for our patients.

We would like to thank the many chapter authors who agreed to write for the Handbook. The time demands on clinical nephrologists continue to increase and we greatly appreciate their willingness to allocate some of their precious time to share their insights and expertise. We also would like to recognize Aleksandra Godlevska for her beautiful modern-art inspired cover art design.

John T. Daugirdas, MD
Peter G. Blake, MB, FRCPC, FRCPI
Todd S. Ing, MD