Medical Education Resources, Inc.

Maximizing Patient Outcomes Through IV Iron Therapy
and Appropriate Iron Measures

CME/CE Internet Program

Please mark and submit your answers on the Posttest / Evaluation Form . After reviewing the web posting carefully, indicate your answers to the quiz questions on the answer sheet. There is only one correct answer for each question. Circle the letter on the answer sheet representing the best answer to each question.

CME Questions

1. Potential effects of iron deficiency include:
a. Pica
b. Restless legs syndrome
c. Impaired thermoregulation
d. All of the above

2. The K/DOQI guidelines recommend a serum ferritin cutoff of _________ for patients with chronic kidney disease.
a. 500 ng/mL
b. >500 ng/mL
c. 800 ng/mL
d. >800 ng/mL

3. What factor(s) should be considered in determining an appropriate serum ferritin level?

a. Safety
b. Benefits
c. Cost-effectiveness
d. All of the above

4. In a study by Finch et al (J Clin Invest. 1976;58:447), _____________ activity in skeletal muscle improved within 4 days of treatment with supplemental iron.
a. Myoglobin
b. Alpha-glycerophosphate
c. Cytochrome a
d. Cytochrome b

5. A study by Chandra et al (Childhood. 1973;48:864) showed iron deficiency in children impaired:

a. Neutrophil function
b. Growth
c. Eyesight
d. Muscle function

6. Which of the following is NOT a benefit of intravenous iron?
a. Enhanced erythropoiesis
b. Correction of the nonhematologic adverse effects of iron deficiency
c. Decreased serum ferritin levels
d. Improved response to erythropoietin therapy

7. Iron content has been shown to be reduced in the _______ of patients with restless legs syndrome.
a. Substantia nigra
b. Liver
c. Heart
d. Leg

8. A study by Martinez-Torres et al (Am J Physiol. 1984;246:R380) demonstrated that impaired body-temperature regulation was associated with:
a. Decreased oxygen consumption
b. Iron deficiency
c. Anemia without iron deficiency
d. Decreased plasma norepinephrine

9. Increases in serum ferritin levels have been correlated with all of the following EXCEPT:
a. Iron storage
b. Inflammation
c. Malnutrition
d. Weight gain

10. A study by Feldman et al (J Am Soc Nephrol. 2004;15:1623) showed there is no association between:
a. Increased risk of death and cumulative iron administration
b. Increased serum ferritin levels and risk of infection
c. Increased serum ferritin levels and risk of inflammation
d. Increased hemoglobin levels and risk of cardiovascular disease

11. Maintenance intravenous iron has been shown to __________________.
a. Increase costs and improve patient outcomes
b. Reduce EPO requirements and improve patient outcomes
c. Increase EPO requirements and improve patient outcomes
d. Reduce costs and reduce serum ferritin level