The New KDOQI Guidelines for Anemia; A Debate
Should an Upper Hgb Limit be Set and What Should it Be?

ASN Renal Week Official Symposium, November, 2006
Setting an Upper Hgb Limit of 13 g/dL is in Our Patients' Interest
Allen R. Nissenson, MD, FASN

The Case for Keeping an Upper Hgb Limit of 12 g/dL
Daniel W. Coyne, MD

Rebuttals and Audience Poll
Audience Questions

Allen R. Nissenson, MD, FASN
Professor of Medicine
Associate Dean
Director, Dialysis Program
David Geffen School of Medicine at UCLA

Daniel W. Coyne, MD
Professor of Medicine
Washington University School of Medicine
St. Louis, Missouri

Brian J.G. Pereira, MD, MBA (Moderator)
CEO and President
Advanced Magnetics, Inc.
Cambridge, MA

This group of talks is accredited for up to 1.5 AMA PRA Category 1 credits™. This group of talks has a single post-test, which must be completed along with an evaluation form to obtain credit. The links to the post-test appear on the individual talk pages.
Date of Web Release: February 27, 2007
CME Credit Eligible Through: April 30, 2008
AMA PRA Category 1 Credits™: 1.5
Target Audiences: Nephrology Board and Recertification candidates practicing nephrologists and internists.
Method of participation: Listen to the talk, read the PubMed abstracts linked to data slides and talk references, take the post-test, read the abstracts linked to post-test answer feedback material.

Guidelines for managing the anemia of renal failure have changed frequently in the last few years. This session, using a "debate format," will elaborate on the indications for iron replacement and how to best dose and deliver erythropoietin. The preferred hemoglobin level will be central to the debate.

Accreditation Statement
The American Society of Nephrology is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

The ASN designates this educational activity for a maximum of 1.5 AMA PRA Category 1 Credits™. Physicians should only claim credit commensurate with the extent of their participation in the activity.

This official ASN symposium was supported by a restricted educational grant from Roche Laboratories, Inc.

The American Society of Nephrology as well as HDCN have conflict of interest policies that requires course faculty to disclose any real or apparent commercial financial affiliations related to the content of their presentations/materials. It is not assumed that these financial interests or affiliations will have an adverse impact on faculty presentations; they are simply noted here to fully inform participants. Speaker disclosures are posted on each individual talk page.

This educational activity may contain discussion of published and/or investigational uses of agents that are not indicated by FDA. The American Society of Nephrology and HDCN do not recommend the use of any agent outside of the labeled indications. Please refer to the official prescribing information for each product for discussion of approved indications, contraindications and warnings. Speaker disclosure about individual talks is posted on each individual talk page.

Participants have an implied responsibility to use the newly acquired information to enhance patient outcomes and their own professional development. The information presented in this activity is not meant to serve as a guideline for patient management. Any procedures, medications, or other courses of diagnosis or treatment discussed or suggested in this activity should not be used by clinicians without evaluation of their patient's conditions and possible contraindications on dangers in use, review of any applicable manufacturer's product information, and comparison with recommendations of other authorities.

To complete this educational activity, the user will need Windows or Macintosh operating software, a connection to the internet with a 28.8 kbps MODEM or better. The computer should have an audio card with speakers. An audio player, either the Windows Media Player from Microsoft or the Flash version 8.0 from Macromedia is required and either can be downloaded for free per instructions on the individual lecture pages. Flash version 8.0 is required for the full-screen slide version of the program. Acrobat Reader is required to print the CME certificate, and this can be download free from

For any questions concerning this specific activity please send an email to or, or call HDCN at 630-325-3276 during normal business hours, Chicago time (Central Standard Time).

For any general questions concerning ASN CME, please contact the American Society of Nephrology.