Contrast Media and CKD:
What You Should Know About Contrast-Induced Nephropathy and Nephrogenic Systemic Fibrosis


ASN Renal Week 2007 Official Symposium
Introduction
Norbert Lameire, MD (moderator)

From Preclinical Evidence to Patient Outcomes Results
Pontus B. Persson, MD, PhD

Audience questions and discussion 1
(Moderator and Faculty)

Imaging Needs in Renally Impaired Patients
Michael V. Knopp, MD, PhD

Nephrogenic Systemic Fibrosis: What we currently know about this new disease entity
Mark A. Perazella, MD

Audience questions and discussion 2
(Moderator and Faculty)




Norbert Lameire, MD
Professor of Medicine from Ghent
Belgium

Michael V. Knopp, MD, PhD
Chairman and Professor
Department of Radiology
Novartis Chair of Imaging Research
The Ohio State University

Pontus B. Persson, MD, PhD
Institute for veg. Physiology
Med. Faculty of Berlin‘s Universities
Charité, Germany

Mark A. Perazella, MD
Associate Professor
Section of Nephrology
Yale University




This group of talks is accredited for up to 1.5 AMA PRA Category 1 credits™. This group of talks has a single post-test, which must be completed along with an evaluation form to obtain credit. The links to the post-test appear on the individual talk pages.
Date of Web Release: January 28, 2008
CME Credit Eligible Through: April 30, 2009
AMA PRA Category 1 Credits™: 1.5
Target Audiences: Physicians, researchers and trainees.
Method of participation: Listen to the talk, read the PubMed abstracts linked to data slides and talk references, take the post-test, read the abstracts linked to post-test answer feedback material.

OVERVIEW :
Imaging the patient wich chronic kidney disease has become more complicated. Radiocontrast agents are associated with acute kidney injury and gadolinium has been associated with nephrogenic systemic fibrosis. This symposium will first review imaging needs in patients with chronic kidney disease. The pathogenesis, epidemiology, outcomes and prevention of contrast induced nephropathy will be reviewed. Finally the association betwen gadolinium and nephrogenic systemic fibrosis will be discussed including current clinical practice guidelines for preventing this devastating complication.

ACCREDITATION AND DESIGNATION STATEMENTS:

Accreditation Statement
The American Society of Nephrology is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

CME Credit Designation Statement:
The American Society of Nephrology designates this educational activity for a maximum of 1.5 AMA PRA Category 1 Credits™. Physicians should only claim credit commensurate with the extent of their participation in the activity.

SPONSORSHIP / SUPPORT :
This official ASN symposium was supported by a restricted educational grant from Bayer HealthCare Pharmaceuticals

FACULTY DISCLOSURE STATEMENTS :
In accordance with the disclosure policies of the Accreditation Council for Continuing Medical Education (ACCME) and FDA guidelines, it is a policy at the ASN for individuals who are in a position to control the content of an educational activity to disclose to the activity participants: 1) the existence of all relevant financial relationships with any commercial interests or other relationships with the manufacturers of any commercial products/devices, or providers of commercial services, that relate to the content of their presentation/materials, or the commercial contributors of this activity, that could be perceived as a real or apparent conflict of interest; for this purpose we consider relationships of the person involved in the CME activity to include financial relationships of a spouse or partner and 2) the identification of a commercial product/device that is unlabeled for use or an investigational use of a product/device not yet approved.

Based on the disclosures provided, the ASN is responsible for identifying and resolving all conflicts of interest prior to presenting the educational activity to the learner. The intent of this policy is not to prevent expert faculty with relevant relationship(s) with commercial interest(s) from involvement in CME, but rather to ensure that ASN CME activities promote quality and safety, are effective in improving medical practice, are based on valid content, and are independent of control from commercial interests and free of commercial bias. In addition, all faculty members were instructed to provide balanced, scientifically rigorous, and evidence-based presentations. (Faculty Disclosure Statement should

Faculty disclosures are posted on each individual talk page.

DISCLOSURE OF UNLABELED USE:
This educational activity may contain discussion of published and/or investigational uses of agents that are not indicated by FDA. The American Society of Nephrology and HDCN do not recommend the use of any agent outside of the labeled indications. Please refer to the official prescribing information for each product for discussion of approved indications, contraindications and warnings. Faculty disclosure about unlabeled or off-label use is posted on each individual talk page.

DISCLAIMER:
Participants have an implied responsibility to use the newly acquired information to enhance patient outcomes and their own professional development. The information presented in this activity is not meant to serve as a guideline for patient management. Any procedures, medications, or other courses of diagnosis or treatment discussed or suggested in this activity should not be used by clinicians without evaluation of their patient's conditions and possible contraindications on dangers in use, review of any applicable manufacturer's product information, and comparison with recommendations of other authorities.

USER INSTRUCTIONS:
To complete this educational activity, the user will need Windows (XP or higher) or Macintosh (version 9.0 or higher) operating software, a connection to the internet with a 28.8 kbps MODEM or better. The computer should have an audio card with speakers. An audio player, either the Windows Media Player (download from www.microsoft.com) or the Flash version 8.0 (download from www.adobe.com) is required, and either can be downloaded for free per instructions on the individual lecture pages. Flash version 8.0 is required for the full-screen slide version of the program. Acrobat Reader is required to print the CME certificate, and this can be download free from www.adobe.com.

For any questions concerning this specific activity please send an email to or email@asn-online.org, or call HDCN at 630-325-3276 during normal business hours, Chicago time (Central Standard Time).

For any general questions concerning ASN CME, please contact the American Society of Nephrology.