HDCN Abstract:  ASN Annual Meeting -- San Francisco  

Donadio C, Halim AB, Khedr B, et al.

In Maintenance Hemodialysis Patients Lean Body Mass Can Be Evaluated by Bioelectrical Impedance Analysis.

ASN Annual Meeting -- San Francisco
J Am Soc Nephrol (Nov) 18:704A 2007

The assessment of the nutritional status of chronic kidney disease patients plays a central role in nephrology practice. In particular, in maintenance hemodialysis (MHD) patients malnutrition is closely related to morbidity and is a predictor of mortality. In MHD patients the analysis of body composition is a key point to assess nutritional status. Dual-energy X-ray absorptiometry (DXA) is a reference method for a detailed assessment of fat mass (FM) and lean body mass (LBM). The reliability of single-frequency bioelectrical impedance (sf-BIA) versus multi-frequency (mf-BIA) to analyze body composition in MHD is debated.

Aim of this study was to evaluate the adequacy of sf-BIA and mf-BIA, in comparison with DXA, to evaluate LBM in MHD patients.Twenty-seven patients (9 f, 18 m), 32-88 yrs, BW 42-94 kg, BMI 17.5- 34.4 kg/m2, on MHD since 0.5-17.4 years participated in this study.LBM was measured, in the interdialytic day, with DXA and BIA. Two different sf-BIA and one mf-BIA analyzer were used.

A very close correlation was found between LBM-BIA and LBM-DXA (R 0.901 - 0.921). Mean values of LBM were very similar with the different techniques. LBM was 45.1.18.8 kg (DXA); 45.18.5 (sf1-BIA); 45.88.8 (sf2-BIA); 44.411.5 (mf-BIA). Prediction errors were 3.4 kg for sf1-BIA, 4.0 kg for sf2-BIA, and 5.0 kg for mf-BIA.

These results indicate that bioelectrical impedance analysis, in particular with single frequency analyzers, is a reliable method to evaluate lean body mass in maintenance hemodialysis patients.

© Copyright 2007-2008, American Society of Nephrology. Reproduced with permission.
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