Donadio C, Halim AB, Khedr B, et al.
In Maintenance Hemodialysis Patients Lean Body Mass Can Be Evaluated
by Bioelectrical Impedance Analysis.
ASN Annual Meeting -- San Francisco
J Am Soc Nephrol
(Nov) 18:704A 2007

The assessment of the nutritional status of chronic kidney disease patients
plays a central role in nephrology practice. In particular, in maintenance
hemodialysis (MHD) patients malnutrition is closely related to morbidity and
is a predictor of mortality. In MHD patients the analysis of body composition
is a key point to assess nutritional status. Dual-energy X-ray absorptiometry
(DXA) is a reference method for a detailed assessment of fat mass (FM) and
lean body mass (LBM). The reliability of single-frequency bioelectrical
impedance (sf-BIA) versus multi-frequency (mf-BIA) to analyze body
composition in MHD is debated.
Aim of this study was to evaluate the
adequacy of sf-BIA and mf-BIA, in comparison with DXA, to evaluate LBM in MHD
patients.Twenty-seven patients (9 f, 18 m), 32-88 yrs, BW 42-94 kg, BMI 17.5-
34.4 kg/m2, on MHD since 0.5-17.4 years participated in this
study.LBM was measured, in the interdialytic day, with DXA and BIA. Two
different sf-BIA and one mf-BIA analyzer were used.
A very close
correlation was found between LBM-BIA and LBM-DXA (R 0.901 - 0.921). Mean
values of LBM were very similar with the different techniques. LBM was
45.1.1
8.8 kg (DXA); 45.1
8.5 (sf1-BIA); 45.8
8.8 (sf2-BIA);
44.4
11.5 (mf-BIA). Prediction errors were 3.4
kg for sf1-BIA, 4.0 kg for sf2-BIA, and 5.0 kg for mf-BIA.
These
results indicate that bioelectrical impedance analysis, in particular with
single frequency analyzers, is a reliable method to evaluate lean body mass
in maintenance hemodialysis patients.

© Copyright 2007-2008, American Society of Nephrology.
Reproduced with permission.
Until September of 2008, all ASN abstracts
from the 2007 Annual Meeting are available at this link.
Disclaimer: Abstracts often have errors, both
typographical and otherwise. This posting is an electronic translation of
submitted abstracts which has not been verified against the original
submitted abstract nor with the authors for accuracy. As a result, there
may be errors, especially with regard to drug doses, but not limited to
these. Abstracts undergo only limited review, and data often are changed
as a result of the peer review process, so their reliability is less than
manuscripts published in peer-reviewed journals. In using these
summaries, you are agreeing that you are aware of these limitations.
The materials are provided on an as-is basis without any warranty of
any kind, either express or implied. In addition to errors, the
information presented may be incomplete or outdated.
The information contained is not intended nor recommended as a substitute
for professional medical advice. You are advised to check the appropriate
medical literature and the product information currently provided by the
manufacturer of each device to be used or drug to be administered to
verify the dosage, the method and duration of administration, or
contraindications. It is the responsibility of the treating physician or
other health care professional, relying on independent experience and
knowledge of the patient, to determine drug, disease, and the best
treatment for the patient.
To the fullest extent permitted by law, HDCN, ASN and their affiliates and
suppliers disclaim all
warranties, express or implied, including, but not limited to, any
warranty of merchantability, non- infringement or fitness for a
particular purpose.
In no event shall HDCN, ASN, or their affiliates or suppliers be
liable for any damages whatsoever (including, but not limited to,
direct, indirect, incidental, consequential, punitive or exemplary
damages, or any damages for loss of profits, use, data, goodwill or
other intangibles) arising from or in any way relating to these terms,
the materials, or any information, goods or services obtained from or
referred to in the materials, whether based on warranty, contract, tort
(including, but not limited to, negligence), or any other legal theory,
and whether or not any or all of the limited entities is advised of the
possibility of such damages.
|