Massy ZA, Ma JQ, Louis TA, Kasiske BL
Lipid-lowering therapy in patients with renal disease

Kidney Int (Jul) 48:188-198 1995

This is a meta-analysis to compare various lipid-lowering interventions in patients with renal disease. Controlled and uncontrolled studies from MEDLINE were included if they addressed therapies including diet, exercise, drugs (including ACE inhibitors and NSAIDs in nephrotic syndrome and LMW heparin in HD pts). Weighted multiple linear regression analysis indicated that HMG-CoA reductase inhibitors decreased LDL by -51 to -84 mg/dl and fibric acid derivatives lowered triglycerides by -69 to -132 mg/dl. Other interventions had inconsistent effects. (Leehey)

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CRF by problem area : Lipids