Bonomini M, Forster S, Derisio F, Rychly J, Nebe B, Manfrini
V, Klinkmann H, Albertazzi A
Effects of selenium supplementation on immune parameters
in chronic renal failure patients on haemodialysis
Nephrol Dial Transplant
(Sep) 10:1654-1661 1995
This study was an attempt to link impaired cellular immunity in dialysis
patients with possible selenium deficiency. Twenty patients were studied in
two cities (Italy and Germany). Half were given selenium supplementation and
half placebo for 6 months. Hypersensitivity was evaluated only in the 10
Italian patients. Supplementation normalized plasma selenium levels, and in
the few Italian patients studied, appeared to improve delayed type
hypersensitivity.
Comment: Obviously much larger studies are required for these
interesting preliminary results to be confirmed.
(Daugirdas)
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CRF by problem area :
Infections (other than hepatitis, peritonitis)
CRF by organ system :
Nutrition