Singh H, Linas SL
Compulsive water drinking in the setting of anticholinergic drug use: an unrecognized cause of chronic renal failure

Am J Kidney Dis (Oct) 26:586-589 1995

Four unusual cases of obstructive uropathy causing chronic renal failure are presented. All four patients had schizo-affective disorders, exposure to drugs with anticholinergic activity, psychogenic polydipsia, and no anatomic lesion causing obstruction. It is postulated that functional bladder outlet obstruction due to anticholinergics combined with excessive urine volumes caused by polydipsia led to chronic renal injury. (Paller)

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ARF etiology : Urinary tract obstruction
Sodium/water transport : Hyponatrenia