HDCN Article Review/Hyperlink

Antonios TFT, Cappuccio FP, Markandu ND, Sagnella GA, MacGregor GA

A diuretic is more effective than a beta-blocker in hypertensive patients not controlled on amlodipine and lisinopril

Hypertension (Jun) 27:1325-1328 1996

Combination therapy with a calcium channel blocker and ACE-inhibitor is now in vogue, with a number of combination pills available on the market. In this study, patients who fail this therapy were given either a diuretic, bendrofluazide 5 mg, atenolol 100 mg, or placebo. The diuretic worked best, better than atenolol or placebo.

Comment: The results underscore the usefulness of diuretic therapy. (John T. Daugirdas, M.D., University of Illinois at Chicago)

The full text of this abstract is available from the AHA at:
this site .