HDCN Article Review/Hyperlink

Jones DC, Hayslett JP

Outcome of pregnancy in women with moderate or severe renal insufficiency

New Engl J Med (Jul) 335:226-232 1996

The authors reviewed the outcomes of 82 pregnancies among 67 women with serum creatinine levels greater than 1.4 mg/dl prior to becoming pregnant. 10 percent of the pregnancies were associated with a rapid deterioration of renal function, but infant survival was 93 percent. Women with an initial creatinine greater than 2.0 fared especially poorly, with 35% suffering progression of renal failure to the point where dialysis was necessary. (jtd)

The abstract of this paper is available from the National Library of Medicine's PubMed site: click here .

For accompanying editorial by Epstein: Click here.