Arduino M
Vision, hearing loss after use of markedly outdated cellulose acetate
dialyzers
CDC Device Query (informal)
(Oct) : 1996

Seven patients hospitalized in a tertiary care center in the United
States recently developed common symptoms seven to 24 hours after
hemodialysis consisting predominantly of persistent vision and hearing
disturbances, headache and paresthesia. Findings on physical exam included
conjunctivitis, corneal opacification and optic neuritis. There were no
immediate symptoms noted during dialysis. The syndrome is associated with
the use of an aged cellulose acetate (CA) dialyzer. No other risk factors
were identified. An investigation is ongoing.
Please contact the Centers for Disease Control and Prevention, Hospital
Infections Program, telephone (404) 639-6413, FAX (404) 639-6459 or e-mail
mgk8@cidhip1.em.cdc.gov if you have information on any similar events
related to CA dialyzers or on the worldwide existence of any CA
dialyzers manufactured prior to 1989.
Matthew J. Arduino
Dialysis and Medical Devices Section
mja4@cidhip1.em.cdc.gov