HDCN Article Review/Hyperlink

Martinez F, Mommeja-Mrin H, Estepa-Maurice L, Beaufils H, Bochet M, et al

Case report. Indinavir crystal deposits associated with tubulointerstitial nephropathy

Nephrol Dial Transplant (Mar) 13:750-753 1998

The abstract of this paper is available from Oxford Press at this site.

See also the ASN 1997 abstract from this same group. Two cases of tubulointerstitial nephropathy are reported in patients treated with indinavir. Renal biopsy showed extensive interstitial fibrosis, and indinavir crystals were found in the collecting tubules. The patients also were taking sulfadiazine or acyclovir. See also the letter to NEJM last year by Tashima et al. (John T. Daugirdas, M.D., University of Illinois at Chicago)