HDCN Article Review/Hyperlink

Lee A

The Helicobacter pylori genome -- new insights into pathogenesis and therapeutics

N Engl J Med (Mar) 338:832-833 1998

This editorial is available from the NEJM: Click here.

What does this have to do with nephrology? Many of our patients can't take oral iron. This editorial describes specific proteins in H. pylori that are highly conserved that target iron avidity. Perhaps our dialysis patients who are intolerant of iron are infected with this organism, and perhaps tolerance to oral iron therapy might be mitigated by eradicative therapy. Just a hypothesis... (John T. Daugirdas, M.D., University of Illinois at Chicago)