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Article Review/Hyperlink |
Davies SJ, Phillips L, Russell GI
Peritoneal solute transport predicts survival on CAPD independently of residual renal function
Nephrol Dial Transplant (Apr) 13:962-968 1998
The interesting feature of this paper was, that survivors and non-survivors initially started out with comparable levels of D/P-creatinine, and then the group that went on to develop increased peritoneal permeability wound up having a higher death rate. The data suggest that glycosylation end product formation in the peritoneum by glucose-containing PD solutions may be operative and an adverse factor; perhaps membrane glycosylation and the resulting increase in permeability could be mitigated by treatment of non-diabetic PD patients with aminoguanidines? (John T. Daugirdas, M.D., University of Illinois at Chicago)
The abstract of this paper is available from Oxford Press at this site.
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