HDCN Article Review/Hyperlink

Davies SJ, Phillips L, Russell GI

Peritoneal solute transport predicts survival on CAPD independently of residual renal function

Nephrol Dial Transplant (Apr) 13:962-968 1998

The interesting feature of this paper was, that survivors and non-survivors initially started out with comparable levels of D/P-creatinine, and then the group that went on to develop increased peritoneal permeability wound up having a higher death rate. The data suggest that glycosylation end product formation in the peritoneum by glucose-containing PD solutions may be operative and an adverse factor; perhaps membrane glycosylation and the resulting increase in permeability could be mitigated by treatment of non-diabetic PD patients with aminoguanidines? (John T. Daugirdas, M.D., University of Illinois at Chicago)

The abstract of this paper is available from Oxford Press at this site.