Bernardini J, Piraino B
Measuring compliance with prescribed exchanges in PD patients
17th Annual CAPD Conference
Perit Dial Int Suppl 1 (Feb) 17:S12 1997

In this important abstract, also presented at ASN in 1996, the authors investigate the relatively neglected issue of noncompliance with exchanges in PD patients. They use what might be considered a gold standard methodology to assess this. This involves two visits to the patient's home, separated by 4-8 weeks. On each occasion an inventory of dialysate is made. Patients who have used less than 90% of prescribed dialysate during the study interval are defined as noncompliant. 20 patients were studied, of whom 15 were on CAPD and 5 on CCPD. 40% were noncompliant, performing a mean of 75% of their exchanges. Sex, race, age and diabetes were not predictors of noncompliance.

Comment: This is an important study, suggesting that noncompliance is even more common than may have been imagined. An obvious strength is the methodology used, which is clearly superior to creatinine excretion ratios or questionnaires. A weakness is the relatively small number of patients tested. This would not make it possible to identify risk factors for noncompliance and larger studies need to be done. Nevertheless, this study emphasizes how frequent and potentially important this problem is. (Peter G. Blake, M.D., Victoria Hospital, London, Ontario)

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17th Annual CAPD Conference
Basic peritoneal dialysis : Chronic PD regimens, adequacy, modeling