Bernstein SP, Griffin EM, Santiflia EM, Kurpen SA, Brady AB,
McMahon MM
Prevention of exit-site infection with hypertonic saline
17th Annual CAPD Conference
Perit Dial Int Suppl 1
(Feb) 17:S92 1997
This study evaluated the use of saline soaks to prevent exit site
infection. Seventy-one patients were studied during a 30-month period.
All patients had single-cuff catheters in place. During the initial
period, exit site care consisted of daily cleaning with a gauze soaked with
normal saline. During the control period, hypertonic saline was used.
Hypertonic saline was prepared by adding 2 tablespoons of table salt to a
liter of sterie saline, giving a 2.25% NaCl solution.
With about 1000 patient months of follow-up in each group, there were 37
exit site infections during the period when normal saline was used vs. only
16 when hypertonic saline was used. The incidence figures were 1:29 vs.
1:66, respectively.
Comment: Problems: No analysis of exit-site infection (ESI). Were
all patients new or did they have a history of previous ESI? Were only
the first ESI counted? How was ESI treated? Nevertheless, this is an old
surgical trick that seems worth a try.
(Stephen Vas, M.D., University of Toronto, Canada)
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