Bower JD, Case G
Total dose iron infusion: a time saving cost effective method
of iron replacement
17th Annual CAPD Conference
Perit Dial Int Suppl 1
(Feb) 17:S79 1997
How best to give parenteral iron remains problematic in home dialysis
patients, as it is impractical to have patients return to the clinic for
multiple IV infusions. Whereas many PD patients, contrary to their
counterparts on HD, can be maintained on oral iron, home patients also
often require iron (although probably less often than center HD patients).
Bower and Case developed the concept of giving a large amount of iron
dextran at a single sitting. They wound up giving 700 mg diluted in 150 ml
of saline, over 45 min to 2 hours to 110 patients, with only 3 mild
reactions.
Comment: This mode of iron administration is not new; e.g., in the
Dialysis Handbook it has been recommended to give 500 mg diluted in 250 ml
of NS to PD patients when required. The safety of IV iron should be
further increased with use of alternative agents to iron dextran (see 1996
ASN abstracts).
(John T. Daugirdas, M.D., University of Illinois at Chicago)
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17th Annual CAPD Conference
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