Hata T, Akiba T, Haneda M, Noda Y, Adachi M, Matsumura Y,
Tachibana K, Matsuda O, Marumo F
CPD using closed-system automated PD is effective in the
treatment of severe acute pancreatitis
17th Annual CAPD Conference
Perit Dial Int Suppl 1
(Feb) 17:S95 1997
A number of anecdotal reports and small series have been contributed
in an effort the support the use of PD to clear substances
(cytokines?, "evil humors"?) associated with pancreatitis. Concern has
been voiced about the introduction or aggravation of infections that may
offset any therapeutic benefit. This abstract describes the prospective
experience with 7 patients (mean Ranson’s criteria score 4.7 out of 11)
treated with closed system automated PD from 9-34 days (average 16).
Only one patient died (of respiratory failure) representing an extremely
low mortality rate (14.2%) compared to 18 historical reports (not
identified in abstract). Ranson’s criteria alone would suggest greater
than 40% mortality.
Comment: A disease process as complex as severe pancreatitis
demands control of a number of confounding variables. Rapid advances in
critical care medicine make historical controls less relevant. This
report failed to define the incidence of PD associated infection or
other morbidity. The use of dialysis for this non-dialytic indication
remains experimental.
(Sri Narsipur, MD, SUNY-HSC at Syracuse, NY)
To go back use the BACK button on your browser.
Otherwise click on the desired link to this article below:
17th Annual CAPD Conference
CRF by organ system :
GI/Liver, Hepatitis