Shetty A, Cole EH, Oreopoulos DG
Post-transplant renovascular thrombosis is not more common in
CAPD recipients
17th Annual CAPD Conference
Perit Dial Int Suppl 1
(Feb) 17:S67 1997
Primary renovascular thrombosis is an important cause of early graft
loss in renal transplant recipients. Risk factors are said to
include diabetes, increased donor age and increased recipient age.
This study was designed to answer the question "Does CAPD predispose
to renovascular thrombosis in transplant recipients?".
519 transplants were studied (Jan 1985 to Aug 1994). The incidence of
renovascular thrombosis was examined, as well as presence or absence
of known risk factors in patients on CAPD (n = 291) versus those on
HD (n = 228). The CAPD group had many more patients with diabetes in
it (26% versus 6%), but the two groups had similar donor and
recipient ages. The incidence of renovascular thrombosis with graft
loss was 5% in the CAPD group and 3% in the HD group, but this
difference was not statistically significant. The authors conclude
that CAPD is not a risk factor.
Comment: The study is presumably retrospective, so one cannot be
sure that the
two groups are strictly comparable. The study is clearly and
concisely presented and the results speak for themselves. However,
there are other aspects of the data that would appear to bear more
analysis. For instance, did those patients who experienced
thrombosis tend to be older, were the their donors older or very
young? Was it the patients with diabetes that suffered thomboses?
Nevertheless, the authors appear to have dealt with the question they
set out to answer, hopefully they will tell us the rest in the paper?
(Alastair J. Hutchinson, M.D., The Royal Infirmary, Manchester,
UK)
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17th Annual CAPD Conference
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