Rossi GP, Sacchetto A, Visentin PA, Graneiro GR, Canali C,
Pessina AC
Left ventricular mass and diastolic function in primary
aldosteronism and primary hypertension
AHA Council for High Blood Pressure Research
Hypertension
(Sep) 26:540 (abst) 1995
The renin-angiotensin system may play a role in cardiac remodelling in
hypertensive patients. AII can cause myocardial cell hypertrophy and
hyperplasia,
whereas aldo may cause interstitial fibrosis and collagen deposition.
Patients
with essential hypertension and primary aldo (n=34 ea) matched with respect
to demographics and BP were compared using echo with respect to LV mass and
diastolic function indices including flow during ventricular diastole (E)
and
atrial systole (A) . Patients with primary aldo had higher LV mass and
reduced
diastolic function (lower area E/A and higher A%). Excess aldo may result
in
increased LV mass and diastolic dysfunction.
(D. Leehey)
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AHA Council for High Blood Pressure Research
H: Special problems :
Endocrine hypertension
H: Exam and lab tests :
Tests for LVH