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HDCN News Archive -- Diabetes
Feb14	Semaglutide shown to effect substantial weight loss in obese persons.
Jul09	Predicing serum K from the EKG trace measured by an Apple watch.
May09	Fournier gangrene of the genitals linked to SGLT2 inhibitor drugs
Jun12	Pharmacologic approach to weight loss that prevents food absorption.
Aug10	Immunotherapy may arrest damage of beta cells in type 1 diabetes.
May24	CRIC study shows a high urinary sodium excretion in CKD linked to higher CV risk.
Apr27	Tetraspanin-7 as an antibody target for type 1 diabete
Dec29	Novel methods to ensure viability of pancreatic islet cells for transplantation.
Dec29	Interleukin-17A may prevent and even reverse diabetic kidney injury.
Dec26	FGF21 suppresses cravings for sweets.
Dec14	Even more news on the new HDCN Facebook page!
Dec14	Some drugs cause weight gain by alterations in the gut microbiome.
Nov30	Combining fasting blood sugar with HbA1c best for detecting prediabetes.
Nov28	Immunotherapy for T1D focusing on regulatory T-cells shows promise.
Nov10	L-DOPA may delay onset of age-related macular degeneration by 8 years.
Sep25	Giving BP meds at bedtime particularly effective in lowering diabetes risk
Sep17	Empagliflozin use in diabetes associated with large reduction in CV risk.
Aug27	FDA approves 2nd PCSK9 inhibitor, Repatha, to lower LDL cholesterol
Aug14	Google partnering with Dexcom in continuous glucose monitoring device.
Jul08	Valsartan combined with sacubitril (neprilysin inhibitor) improves heart failure patient survival.
Apr23	Long coding RNA found that regulates brown fat production
Apr21	Subcutaneous islet cell transplantation holds promise
Feb21	US Government radically changing dietary advice
Feb05	Rapid and unexpected weight gain after fecal transplant
Jan09	Monthly dose of PCSK9 inhibitor lowers serum cholesterol
Oct12	Harvard scientists produce insulin-producing pancreatic beta cells on a large scale.
May29	Samsung plans to open source digital health gadgets.
May07	FDA and the Heart Association and other agencies fight over aspirin
Apr22	Have we found the cure for atherosclerosis? D-PDMP a potential candidate.
Apr22	New test detects diabetic retinopathy at an early stage.
Apr16	Diabetes complication rate in the U.S. shows a sharp decline.
Apr15	Chromium supplements of no benefit in lowering blood sugar
Mar29	Evolocumab lowers LDL cholesterol by more than 50% (NEJM)
Mar29	New class of anticholesterol drugs lowers LDL by 50%
Mar13	Smartphones used to take images of the eye for sharing with health providers.
Mar02	Rare gene deletion that protects the obses against type 2 diabetes identified.
Jan17	Google's smart contact lens project to be piloted to monitor blood sugar levels.
Jan14	New device informs treatment of sleep apnea.
Dec23	Portable retinal scanner developed for early detection of eye disease.
Nov25	FDA removes certain restrictions from Avandia.
Sep25	Melatonin stimulates brown fat formation.
Sep18	Toronto study suggests that CABG is better than stent for diabetic patients.
Sep02	Study of saxagliptin for diabetes shows no increase in heart attack risk.
Aug13	Scientific American reviews the evidence against fructose, and finds little.
Jul05	Salsalate lowers blood glucose in type 2 diabetes.
Jul05	DHA (in fish oil) reduces inflammation via maresin in macrophages.
Jul05	Blocking CD36 might affect inflammation-induced atherosclerosis
Jun26	Reverse DNA vaccine improves pancreatic function in type 1 diabetes.
Jun25	NEJM: Intentional weight loss in overweight type 2 diabetic subjects shows no benefit on death or CV endpoints.
Apr26	Betatrophin may markedly increase insulin production in diabetes.
Mar17	Olive oil plus yogurt combo most effective in achieving satiety.
Feb16	Dogs cured of type 1 diabetes by gene therapy.
Feb16	Off-patent generic drug amlexanox may beneficially affect diabetes.
Jan21	Regular aspirin use associated with risk of age-related neovascular macular degeneration.
Dec06	Aspirin tablet coatings may give rise to aspirin pseudoresistance.
Nov05	NEJM: Coronary revascularization better than percutaneous procedures for diabetic patients.
Nov05	Nabilone shows benefits in managing pain of diabetic neuropathy.
Oct19	Daily vibration combats prediabets in young mice.
Oct09	Bariatric surgery gives disappointing results in terms of sleep apnea.
Oct04	Cost-efficacy of diabetes screening called into question.
Sep19	Compound found in purple corn reduces macrophage activation in diabetic nephropathy in mice.
Sep19	Oral insulin use delays appearance of type 1 diabetes.
Sep07	Miniature glucose sensor may eliminate the need for needlesticks.
Aug09	Thinner diabetics face higher death rate.
Aug09	Do neutrophils mediate insulin resistance in obesity?
Aug07	Is there an obesity paradox in diabetes?
Jul23	Higher serum bicarbonate associated with lower type 2 diabetes risk in Nurses Health Study.
Jul21	New body shape index, based on height, BMI, and waist circumference, predicts mortality risk.
Jul18	FDA approves second diet drug within a month.
Jul12	Circadian clock cryptochromes tied to development of type 2 diabetes.
Jul12	Cucurmin reduces incidence of type 2 diabetes in randomized control trial.
Jul05	Short course of immunotherapy reverses type 1 diabetes in mice.
Jul05	Metformin may boost brain function via stimulation of new neuron formation.
Jun20	Intestinal bacteria secrete neurotransmitters (GABA) that may play a role in inflammation.
Jun13	Study of childhood type 2 diabetes reports unusually high incidence.
Jun13	Thiazolidinedione use may increase risk of macular edema.
Jun07	Why exercise has a beneficial effect on neuropathic pain.
Jun01	Actos (pioglitazone) and bladder cancer risk: tempest in a pee-pot?
Jun01	Study vindicates Atkins type diet in terms of kidney function.
May29	Intensive glucose control in diabetes does not retard CKD progression (meta-analysis).
May14	Another study shows potential benefits of a higher fat diet in diabetic patients.
May01	Diabetes per se may not be a risk factor for contrast nephropathy.
Apr26	FDA issues safety warning about using aliskiren plus an ACEI or ARB in diabetes or CKD.
Apr10	Higher blood glucose levels may benefit heart failure patients.
Apr05	DXA scans suggest that BMI markedly underdiagnoses obesity prevalence in the U.S.
Apr05	As yet unidentified factor from fat stem cells can markedly increase glucose uptake in muscle.
Apr05	Salivary amylase levels determine blood glucose response to starchy food ingestion.
Mar13	Mouse intestinal cells induced to secrete insulin, resulting in possible cure for type 1 diabetes.
Mar08	FDA considering making many drugs over the counter.
Mar08	New class of drugs can reverse fibrosis in injured and diabetes-afflicted kidneys.
Feb26	Takeda's GP40 agonist drug lowers blood sugar in type 2 diabetes without hypoglycemia risk.
Feb22	FDA advisory panel votes to approve weight loss drug Qnexa (phentermine/topiramate)
Feb21	Link between polyneuropathy and prediabetes questioned.
Feb21	Annals review of controlled feeding trials debunks idea that fructose leads to obesity.
Feb18	New link identified between insulin resistance ant gut inflammation via fatty acid synthase.
Feb07	Is obesity and nonalcoholic fatty liver disease contagious?
Feb07	Taste receptor type cells in the pancreas release insulin in response to fructose.
Jan18	Mechanism of anticancer effect of metformin explained.
Jan12	What is irisin and how does it regulate brown fat tissue?
Dec06	Rotating night shift work increases risk of type 2 diabetes in women.
Nov16	Niacin may not improve hard outcomes.
Nov09	Tear drops as useful as blood for monitoring blood glucose levels (in rabbits).
Nov09	Potassium channels in the hypothalamus linked to blood glucose control.
Oct31	Extracorporeal shock wave therapy gives encouraging results in male impotence.
Oct28	Sulodexide fails to show benefit in diabetic kidney disease in large trial.
Oct14	ASN Renal Week 2011 abstracts now available.
Oct14	Bacteria-derived bile acids linked to efficacy of statins.
Oct06	Diabetic rats cured with their own stem cells
Sep18	Risk of pancreatitis and pancreatic cancer with sitagliptin and exenatide highlighted.
Sep15	ADVANCE trial results suggest that intensive glucose control slows progression to ESRD in diabetic patients.
Sep07	CDP138 protein involved in insulin-stimulated insertion of GLUT4 into cell membrane.
Aug30	Weight-loss simulatino tool allows prediction of efficacy of dietary interventions for obesity.
Aug23	New computed tomography heart scan exposes patients to 90% less radiation.
Aug19	Sirtuin activating drug prolongs lifespan in obese mice by 45%
Jul23	Metformin can reduce risk of polycystic ovary syndrome in susceptible young girls.
Jul21	FDA panel votes against dapagliflozin, casting doubt over the drug class of SGLT2 inhibitors.
Jul15	European studies find few benefits of near-normalization of blood glucose in type 2 diabetes.
Jul12	Eating tree nuts helps diabetic patients lower HbA1c levels.
Jul01	New class of antiangiogenesis drugs discovered from South American tree.
Jun28	Visceral fat decreased by increased intake of soluble fiber and exercise.
Jun28	NEJM: Bardoxolone methyl improves kidney function in type 2 diabetic patients.
Jun25	ADA Scientifc Sessions, June 2011. Home page and daily newsletter.
Jun25	American Diabetes Association Scientific Sessions - abstracts online
Jun25	BCG vaccine and the spleen: Both involved in a potential cure for type 1 diabetes?
Jun24	Eight week diet of 600 kcal/day can reverse early type 2 diabetes
Jun16	FDA Medwatch: Ongoing safety review in progress re pioglitazone and possible bladder cancer risk.
Jun13	FDA Medwatch: Risk of thyroid calcitonin tumors (in rodents) and pancreatitis with liraglutide.
Jun10	France and Germany suspend approval for pioglitazone due to bladder cancer risk question; other countries not yet.
Jun10	Inhibition of insulin degrading enzyme may help control type 2 diabetes.
Jun07	Gene therapy reverses type 1 diabetes in mice.
May19	Avandia (rosiglitazone) REMS (Risk Evaluation and Mitigation Strategy) document.
May19	More on Avandia action by the FDA
May19	FDA pulls Avandia (rosiglitazone) from retail pharmacy shelves.
May17	FDA advisory panel will convene to reconsider approval of fenofibrate
May16	KLF14 gene may be a regulator of body fat, obesity, and cholesterol.
May03	Sodium retention action of thiazolidinediones linked to increased proximal tubular absorption.
May03	Link to EPOGH study in JAMA on urinary sodium and CV death risk.
Apr29	Review of non-nutritive sweetners from the Diabetes Care journal
Apr29	Avastatin equivalent to Lucentis for treating wet macular degeneration, but much cheaper.
Apr28	Vitamin E helps reduce nonalcoholic fatty liver more than metformin in diabetic kids.
Apr22	Ketogenic diet reverses diabetic nephropathy in mice.
Apr22	Pirfenidone gives promising results in treating diabetic nephropathy.
Apr19	A mother's diet during pregnancy can alter a baby's DNA.
Apr15	Apparent link between diabetes and diet soda may be confounding by indication.
Apr12	Am Acad Neurol issues guidelines regarding treatment of diabetic nerve pain.
Apr07	Ciliary neurotropic factor delivered by encapsulated cells may help age-related macular degeneration
Mar29	Very high fish oil consumption may protect obese persons from inflammatory-related complications.
Mar29	Phase 1 safety trials for begin for deuterium-based drug targeting diabetic kidney disease.
Mar29	Nicotine found to increase blood levels of HbA1c in diabetic patients.
Mar24	Blood levels of 5 metabolites can predict subsequent development of type 2 diabetes
Mar24	Ok, you know about FGF23. But FGF19 may be even more important in glucose metabolism.
Mar24	NEJM: Pioglitazone lowers (by 72%) the risk of progression of impaired glucose tolerance to type 2 diabetes
Mar15	11beta-hydroxysteroid dehydrogenase type 1 linkes to apple vs. pear-shaped phenotype.
Mar15	Testing tears for glucose content may be alternative to skin-prick monitoring.
Mar15	Snapin protein found to control insulin release from pancreatic beta cells.
Mar12	Endothelin-A antagonist atrasentan reduces UACR in diabetics in small phase 2 study.
Mar12	Disruption of circadian cycle can lead to fatty liver.
Mar02	New analysis of ACCORD study finds increased mortality with tight glucose control.
Mar02	Higher diabetes risk in African Americans linked to lower serum potassium levels
Feb28	Gut bacteria can affect hepatic lipid metabolism
Feb24	Dietary sodium has a U-shaped association with CKD progression in type 1 diabetes
Feb24	FDA approves saxagliptin (Onglyza) labeling to include patients with CKD
Feb24	Missing sugar molecule raises diabetes risk in humans
Feb16	Metformin for CKD? A contrarian point of view.
Feb07	Pivotal discoveries in age-related macular degeneration.
Feb01	Specific populations of bacteria in the gut linked to fatty liver.
Jan31	New USDA sodium guidelines recommend sodium intake < 1.5 g/day for individuals with CKD, HTN, or DMj
Jan27	Who needs insulin? UT Southwestern study shows that without glucagon, insulin may not be that important.
Jan23	Ain't necessarily so: Why are people in developed countries obese, again?
Jan21	Inhaled insulin fails to get FDA approval; 2 additional studies were requested.
Jan15	National Library of Medicine's Daily Med website for quick access to drug package inserts.
Jan14	Coffee, sex (hormones), and diabetes...
Jan11	New obesity drug shows stunning rate of weight loss in pilot study.
Dec22	Metreleptin a promising new treatment for type 1 diabetes.
Dec21	Ain't necessarily so dept: Whole fat dairy product fatty acid associated with lower risk of type 2 diabetes.
Dec16	Seaweed-coated pig islet cell transplantation approved to treat type 1 diabetes in Russia.
Nov30	M3 muscarinic receptor on pancreatic beta cells key to insulin release.
Nov08	Rush to judgement? Rosiglitazone not linked to heart events in BARI 2D
Nov08	Pentazocine stabilizes retina in a mouse model of diabetes.
Nov02	MMWR: Diabetes accounts for 44% of new cases of ESRD.
Nov02	Inhaled steroids increase diabetes risk.
Nov02	New liver hormone linked to selenoprotein P associated with insulin resistance.
Oct28	MMWR: Diabetes rates up, but incidence of ESRD due to diabetes is down.
Oct27	Drinking sugary beverages markedly increases risk of diabetes.
Oct25	Diabetics resistant to diabetic retinopathy have low levels of tyrosine phosphatase SHP-1
Oct18	Fenretinide reduces the risk of transformation of dry to wet macular degeneration.
Oct15	NEJM: Regulatory action on rosiglitazone by the FDA.
Oct15	Not-for-profit TOPS weight loss program found to be effective.
Oct09	Abbott removes weight loss drug Meridia (sibutramine) due to stroke and heart disease risk.
Sep30	Strong link found between diabetes and air pollution.
Sep25	Increased magnesium intake associated with a lower incidence of diabetes
Sep23	FDA says, US patients will only be allowed to take rosiglitazone if they are unable to take pioglitazone.
Sep23	FDA to limit patient access to rosiglitazone (Avandia)
Sep23	European Medicines Agency recommends that Avandia (rosiglitazone) be banned from the European market.
Sep10	University of Kansas researchers develop compound that reverses diabetic neuropathy in mice.
Sep08	Long-term weight loss may increase blood levels of fat-soluble organic pollutants.
Sep07	Vegetable-based low-carbohydrate diets better than those rich in animal protein
Sep03	Fish oils inactivate inflammatory effects of macrophages present around fat cells
Sep02	NEJM: Increased cardiovascular risk from weight loss drug sibutramine.
Aug26	Analysis of large claims-based dataset suggests heart risks for rosiglitazone and pioglitazone are similar.
Aug26	Naringenin from grapefruits shows promise as a treament for type 2 diabetes
Aug24	Randomized trial shows that drinking water before a meal reduces calorie consumption.
Aug17	Bariatric surgery markedly improves type 2 diabetes
Aug02	Low carb diet boosts HDL cholesterol more than low fat diet over 2-year period.
Jul22	Osteocalcin and bone intimately involved in diabetes and insulin action.
Jul21	FDA freezes enrollment in pioglitazone vs. rosiglitazone safety study.
Jul21	Glitazones act NOT as PPAR-gamma agonists, but by blocking PPAR phosphorylation by ckd5.
Jul20	Inhaled insulin comes one step closer to FDA approval.
Jul15	FDA review panel shows mixed opinions about whether Avandia should be withdrawn from sale.
Jul15	ACCORD (NEJM): HbA1c target < 6% and combo statin/fenofibrate Rx better for retinopathy.
Jul12	Fatty acid elongase cures type 2 diabetes in mice.
Jul09	More on the FDA and Avandia (rosiglitazone) safety issues.
Jul08	Rosiglitazone safety issues continue to be unresolved. FDA to reveal new data tomorrow.
Jul08	What is oh-GLICK-nack-ase and why is it important?
Jul06	Got a thick neck? Might not be so good if you're a child.
Jul06	Obesity-induced inflammation linked to !L-6 generation via adipocyte PCK-zeta.
Jul06	INVEST study published in JAMA: No benefit of targeting BP < 130/80 in diabetics vs. 130-140
Jul02	Honey as a topical antibiotic explained.
Jun29	Can't decide if rosiglitazone is safe for the heart? Ask Consumer Reports.
Jun29	Video presentation summary of ACCORD trial results.
Jun29	New study shows no increased cardiovascular risk due to rosiglitazone.
Jun29	ACCORD trial results with HbA1C < 6% show some benefits, some risks.
Jun29	ACCORD trial shows eye benefits of intensive glucose control and of statin+fibrate therapy.
Jun29	American Diabetes Association 2010 meeting abstracts
Jun22	ENDO 2010 "abstracts 2 view"
Jun22	Daily new reports of ENDO 2010 meeting
Jun22	Cutting carbs more effective than low-fat diet in insulin-resistant women.
Jun17	Once-weekly exenatide controls weight and HbA1c in DURATION-4 study.
Jun17	Has the cause of type 1 diabetes been found?
Jun15	Hemoglobin A1c levels slightly higher in African Americans.
Jun10	Allopurinol markedly slows progression of CKD in small randomized trial.
Jun02	World-wide standardization for HbA1c is in the works.
Jun02	Nicer than needles: insulin pills for diabetics in clinical trials.
May26	Enterovirus gene fragments found in 83% of kids with type 1 diabetes.
May21	Weekly GLP-1 mimetics soon to be available for diabetics.
May21	Long-term metformin use linked to vitamin B12 deficiency
May21	Nanotech breath sensor for acetone detects type 1 diabetes.
May12	Gum disease treatment may help glucose control in patients with diabetes
May05	A single sleepless night can induce insulin resistance in healthies.
Apr30	NEJM: Vitamin E good for nonalcoholic steatohepatitis (NASH)
Apr28	Eating hot peppers significantly increases (doubles) post-prandial energy expenditure as well as fat oxidation.
Apr28	RCT shows that high-dose B vitamins associated with increased risk of progression and CV events in diabetics.
Apr15	Premeal ingestion of whey protein suppresses food intake and post-prandial insulin.
Apr14	New artificial pancreas pump infusing both insulin and glucagon controls blood sugar better.
Apr11	Nanovaccine stops type 1 diabetes from developing in mice.
Mar24	Diabetes and prediabetes at epidemic proportions (240 million !) in China
Mar23	Utility of metabolic syndrome as a clinical tool debated in Diabetologia journal.
Mar23	High-fructose corn syrup associated with liver scarring in patients with NAFLD.
Mar22	High fructose corn syrup = table sugar in terms of fructose content, but not in terms of obesity.
Mar15	Valsartan and nateglitidine of no use in reducing CV death in prediabetics.
Mar15	ACCORD trial combination fibrate plus statin results (NEJM, pdf)
Mar15	ACCORD trial lower BP target results (NEJM, .pdf)
Mar15	ACCORD trial results released at ACC: BP lower than 120 or addition of fibrates have no benefit in diabetics.
Mar12	Early initiation of metformin in type 2 diabetes may have advantages.
Mar04	Pycnogenol (pine bark extract) reduces kidney damage in hypertension.
Mar04	NEJM: Glycated hemoglobin linked to CV death risk in nondiabetic adults.
Feb23	AHA/ACC issue Science Advisory re heart risk and thiazolidinedione drugs.
Feb17	Dr. R.H. Lustig on fructose, obesity, and metabolic syndrome (90 min talk)
Feb16	Something fishy about metformin
Feb11	GLP-1 analogue designed to be taken weekly shows promising results in diabetics.
Feb10	Statins associated with a 40% reduction in risk of cataracts
Feb10	Thiazolidinediones increase fracture risk in observational study.
Jan29	Overweight elderly live longer.
Jan26	AJKD: Comments on AURORA study results on use of statins in CKD patients.
Jan21	New sensor can measure glucose in exhaled breath
Jan13	Sophisticated insulin pump prototype in development for type 1 diabetes mellitus
Jan11	CV and kidney progression risk tied to proteinuria may be affected by race.
Jan07	UCLA study shows metformin to be safe in patients with diabetes and advanced heart failure.
Jan06	Candesartan prevents proliferative gene profile in diabetic eye disease.
Dec29	Risk of ESRD in diabetics has been decreasing by 4% per year since 1996.
Dec29	Am Diabetes Assoc promoted increased use of Hb A1C to diagnose diabetes.
Dec23	Intestinal liner to treat type 2 diabetes and obesity approved for sale in Europe.
Dec09	Australia lifts ban on xenotransplantation.
Nov27	Diabetes expected to double, costs to triple, by 2034 in the United States.
Nov26	Rituximab helps preserve beta cell function in patients with early type 1 diabetes.
Nov25	Feeding time a major factor on gene induction circadian variability
Nov24	Diabetics show alarming increase in morbid obesity
Nov24	CDC issues prevalence maps by county for obesity and diabetes
Nov18	Niacin plus statin no better than niacin alone in elderly patients with CAD.
Nov14	Excessive ingestion of selenium supplements can increase cholesterol by 10%
Nov14	Getting fat recently? Maybe too many Firmicutes bacteria in your gut.
Nov05	Glucose may have a life-shortening effect in worms (and maybe humans).
Nov04	Wolfing down food may be one reason people are getting fat.
Nov04	Steamed food diet may be best for CKD patients due to lower AGE content.
Nov03	FDA warns about adverse renal effects of Byetta (exenatide)
Oct07	Cytochrome P450 gene variants markedly influence response to sulfonylureas in diabetics.
Oct01	JASN: Pioglitazone prevents age-related decline in renal morphology and function.
Sep25	Januvia (sitagliptin) linked to increased pancreatitis risk
Sep24	200g/day fructose supplement increases systolic BP by 6 mm Hg, prevented by allopurinol.
Sep24	AJKD issues containing KDOQI guidelines now freely available as .pdf files
Sep18	Metformin or insulin do not lower levels of inflammatory markers in diabetics.
Aug28	New gene controlling formation of adipocytes identified.
Aug28	Mildly heated high-fructose corn syrup generates undesirable chemical compounds.
Aug24	Mice eating a low-carb diet show increased atherosclerosis and decreases in vascular progenitor cells.
Aug24	Is reduction in liver fat the key to the benefits of an alternate-day diet?
Aug24	FDA announces ongoing monitoring of liver injury associated with Orlistat.
Aug24	American Heart Association recommends limiting intake of foods with added sugars.
Aug21	Seasonal variation in amount of brown adipose tissue linked to amount of daylight exposure.
Aug20	Half of type 1 diabetics manifest abnormal immune response to wheat proteins.
Aug19	Heart failure risk with rosiglitazone double that with pioglitazone.
Aug13	Toray develops insulin nasal spray.
Aug13	FDA warns on certain glucose test strips due to interfering sugars.
Aug12	Carnitine supplements improve glucose tolerance in obese rats.
Aug11	Anti-RAS drug restores insulin production in animal model of diabetes.
Aug03	Metformin reduces risk of pancreatic cancer by 60%.
Jul31	FDA approves saxagliptin for use in type 2 diabetes.
Jul31	Avasting (bevacizumab) may be potent treatment for diabetic macular edema.
Jul31	Cataract surgery accelerates diabetic retinopathy.
Jul28	How do drugs like cromolyn that affect mast cells affect adipocytes and metabolic syndrome?
Jul28	Deferoxamine to treat diabetic foot ulcers? In mice, yes.
Jul28	Follow-up of DCCT trial shows 50% lower complications in tight glucose control group.
Jul23	Clinical trial of injecting pig insulin-producing cells into humans begins.
Jul21	In diabetics with heart failure, HbA1c levels of 7.1 to 7.8 at lowest risk of death; tighter control bad.
Jul13	Citrus-derived flavonoid prevents obesity and metabolic syndrome in mice.
Jul08	Is PEDF "the" link between obesity and type 2 diabetes?
Jul07	Safflower oil or CLA supplements lower truncal or total body fat in diabetic women
Jul06	Laser therapy offers a breakthrough in prevention and treatment of early macular degeneration.
Jul02	Newspaper comic strip to target diabetes awareness among Hispanics.
Jul02	U.S. obesity problem intensifies.
Jul02	FDA reviewing safety data for Lantus (insulin glargine) in view of reports of increased cancer risk.
Jul02	Enalapril or losartan markedly slow progression of eye damage in type 1 diabetics.
Jun24	Analysis of large number of bariatric surgery patients shows the procedure to be relatively safe.
Jun19	Inhibition of sirtuin gene by antisense technology improves diabetes in an animal model.
Jun19	Clopidogrel may increase risk of death in patients with diabetic nephropathy.
Jun13	Higher vitamin D levels associated with successful weight loss in obese subjects on a diet.
Jun13	Endocrine Society 2009 meeting (June 10-13) abstracts on-line.
Jun05	ADA Scientific Sessions 2009: Late-breaking abstracts handout
Jun05	ADA 2009 Scientific Sessions newsletter: Preview Edition
Jun05	American Diabetes Association 69th Sessions 2009 in New Orleans (home page)
May30	Continuous glucose monitoring in diabetes: Free journal supplement (17 articles)
May25	Search all abstracts from the World Congress of Nephrology 2009
May22	Fenofibrate reduces amputation risk in diabetics.
May15	Use of CT angiography in the emergency room to help diagnose chest pain found to be cost-effective.
May15	High triglyceride levels associated with diabetic neuropathy
May15	Metformin shown to act directly via CBP glucose-regulating protein in the liver.
May11	Vitamins C and E block improvement of insulin sensitivity with exercise.
May08	CJASN early release: Risk of hypoglycemia doubled in diabetic patients with CKD.
May08	Combining dieting with exercise while standing/sitting/kneeling on a vibration plate machine lowers abdominal fat.
Apr30	Januvia (sitagliptin) pancreatitis risk suggests potential drug class effect on the pancreas for GLP-1 enhancers.
Apr23	Mitochondrial peptide Humanin (HN) strongly affects insulin sensitivity.
Apr23	Low-sodium vegetable juice may help reduce body fat in patients with metabolic syndrome.
Apr22	Alzheimer beta-amyloid can be degraded, and some drugs can increase breakdown rate 7-fold.
Apr18	New stem cell treatment for age-related macular degeneration in development.
Apr16	Heart risk in diabetics may be exaggerated.
Apr12	CXCL5, secreted by white adipose tissue, may be the link between obesity and inflammation and insulin resistance.
Apr12	Eccentric viewing techniques help some patients with age-related macular degeneration read.
Apr11	Three papers on brown adipose tissue in this week's NEJM.
Apr11	One thousand 2007-2009 audiofiles and slide/audio talks added to HDCN's 20 topic-related channels.
A09	Joslin study shows adults have more brown fat than previously thought.
A09	TGF-beta a good guy in maintaining integrity of retinal blood vessels.
A09	Why premature application of guidelines may be dangerous
A07	Chemokine CXCL5, produced by fat cells, linked to inflammation and insulin resistance.
A06	Chlorthalidone increases SNS activity, spironolactone does not
A02	Consumpton of sugary beverages associated with weight loss or weight gain.
A02	Glitazones linked to diabetic macular edema
M30	Lipoic acid supplements markedly lower triglycerides in an animal model.
M30	AURORA study confirms the 4D study: Statins of no benefit in dialysis patients.
M29	Link to slide/audio and audio symposia on HDCN
M25	Synsepalum dulcificum berry turns sour taste to sweet temporarily. May increase appetite in chronically ill.
M22	FDA cautions of hepatitis, other infectious disease, risk from sharing insulin pens
M19	DNA-dependent protein kinase of key importance in metabolic regulation, esp. fat synthesis from CHO.
M12	HDL levels and glucose sensitivity linked to neck circumference.
M12	Low serum 25,D levels associated with higher BP and metabolic syndrome in teenagers.
M06	Signs of enterovirus found in pancreases of 60% of children with type 1 diabetes, but rarely in controls.
M04	Night shift work adversely affects leptin levels and insulin resistance.
M03	PGC-1b gene knockout prevents fructose-fed mice from developing insulin resistance.
F27	FDA warns of tardive dyskinesia risk with Reglan (metoclopramide)
F25	NEJM: Randomized trial of 4 different diets (low fat, low CHO, etc.) fails to find a single winner.
F20	Avosentan cuts urinary albumin excretion in diabetics.
F17	CMS to cover bariatric surgery in obese type 2 diabetics.
F13	Fructose-sweetened drinks increase postprandial serum triglycerides more than when glucose is used.
F13	New tattoo ink changes color according to glucose level; could be used to monitor blood sugar in diabetics.
F10	Vigorous exercise (running) may reduce the risk of age-related macular degeneration.
F09	LSR, lipolysis-stimulated lipoprotein receptor, found to be deranged in type 2 diabetes with obesity.
F04	Arginine discovery may help fight human obesity.
F03	Short-term growth hormone treatment attenuates muscle loss after bariatric surgery.
J28	Four 30-second sprints on an exercise bicycle 3/week improve insulin effect - muscle glycogen depletion?
J20	Low carb diet lowers liver fat better than standard low calorie diet
J19	Three new genes linked to childhood obesity identified.
J17	Diabetes cure in 5 years? These genetically-altered pigs could be the answer.
J16	Mutations in gene regulating melatonin-mediated insulin secretion increase type 2 diabetes risk
J13	Human beta cells can easily be induced to replicate.
J10	Latest U.S. survey shows 1/3 obese, 1/3 overweight.
J09	Human insulin produced by genetically modified safflower plants ready for testing.
J07	Atkins-style low-carbohydrate ketogenic diet superior in controlling blood glucose in type 2 diabetics.
J01	New Year's Resolution? Quit smoking. American Lung Association support info.
J01	Cognitive decline associated with aging linked to higher blood glucose levels in nondiabetics.
D23	Thiazolidinediones associated with higher fracture risk in diabetic women.
D19	Hexokinase-1 gene variations associated with HbA1c levels
D19	Low glycemic index diet improves lipid profile in diabetics
D18	FDA raises the bar for new diabetes drugs
D17	Longitudinal study shows infants and children who will later develop type 1 diabetes exhibit prior metabolic abnormalities.
D15	Lithonia, GA school sugar-free for 10 years with positive results.
D15	Coke to market a new soft drink sweetened with stevia. Pepsi waiting for the FDA.
D14	Study in the Amish links APOC3 gene mutation, triglycerides, and resistance to heart disease.
D11	Fructose metabolism engages the liver in complex and possibly not beneficial ways.
D11	CJASN: Rosiglitazone may benefit patient with FSGS
D11	NEJM: Type 1 diabetes and celiac disease may share a common immunologic mechanism.
D11	Low carbohydrate diets affect cognition skills.
D11	Studies in animals confirm addictive properties of sugar.
D11	Glitazones lower bone density substantially in women but not in men.
D09	Hapless roundworms that don't dauer well yield clues about a fat-burning enzyme
D04	Liver fat, rather than abdominal fat or shape, may be main cardiovascular risk.
D02	Depression increases risk of subsequent visceral fat gain in longitudinal study.
N27	Mechanism of how the brain senses fatty foods identified.
N26	Vitamin K deficiency linked to insulin resistance in older men
N18	Anticancer drugs sunitinib and imatinib cause remission of type 1 diabetes in mice.
N09	Rosuvastatin given to patients with normal cholesterol levels but high CRPs markedly lowers CV risk.
N07	Covidien recalls miscalibrated insulin syringes (overdose risk!) sold at Wal-Mart and Sam's Club.
N04	Intraocular anti-VEGF drugs to treat retinal proliferative disoders may have a dark side.
N04	New SIRT1 activating drug may protect against diet-induced obesity.
N04	Incidence of proteinuria reduced in those diabeics who eat fish at least once a week.
O30	CDC issues new count of diabetes in the U.S. by state. Overall rate nearly doubles.
O30	Alpha-1-antitrypsin treatment improves success rate of pancreatic islet cell transplants.
O29	Animal studies suggest potential benefits of drug holiday for patients taking sulfonylureas.
O27	Costs of treating diabetes has nearly doubled in past 7 years.
O27	Pentoxifylline lowers proteinuria alone or in addition to an ACE inhibitor.
O23	European watchdog agency suggests not using diet drug rimonabant due to depression side effects.
O23	New diet drug tesofensine appears to be remarkably effective.
O22	Japanese study finds that eating quickly doubles risk of obesity.
O17	Risk/benefit ratio of preventive use of aspirin in diabetic patients called into question.
O16	Fructose feeding induces high triglycerides and leptin resistance in rats.
O14	Alpha-1-antitrypsin therapy expands beta-cell populations in the pancreas of mice with a model of type 1 diabetes.
O13	A series of abstracts presented at CRF meeting suggesting that triple anti-platelet therapy (adding cilostazol) improved outcomes.
O09	New physical activity guidelies: 30 minutes of moderate exercise 5 times per week;
O08	10-year follow-up shows prolonged benefits of tight glucose control with sulfonylurea or metformin in UKPDS
O07	Study illustrates importance of inflammatory macrophages in obesity; insulin resistance reversed by killing these cells.
O07	One mechanism whereby ingestion of fatty foods (but not carbs or protein) can suppress hunger identified : OEA.
O07	Gut bacteria may protect mice against type 1 diabetes, other autoimmune disorders.
O06	Just one session of exercise improves metabolic health in insulin-resistant obese subjects.
O06	Adipocyte precursor cells identified, opening up a new area of obesity research.
S26	Aptly named horny goat weed found to be a source of specific phosphodiesterase inhibitors.
S25	Diabetic gastroparesis in mice reversed by restoring defective hemo oxygenase production.
S25	Pentazocine appears to dramatically prevent diabetic retinal damage in mice.
S22	Exercise program cuts liver fat by 40% in type 2 diabetics.
S22	6 months of caloric restriction and 10% body weight loss does not cause young overweight adults to lose bone.
S18	Thin men more vulnerable to osteoporosis.
S16	NHANES data analysis links elevated urine bisphenol levels to diabetes, cardiovascular disease.
S16	Chamomile tea cuts diabetes complications (in rats)
S10	Pentazocine shows encouraging results in a mouse model of diabetic retinopathy.
S10	NEJM early release: Benefits of tight glucose control persist in type 2 DM at 10 years
S10	NEJM early release: Tight BP control has to be continued in type 2 diabetics; otherwise benefits are not maintained.
S08	Once-a-week sustained release exenatide lowers HbA1c better than twice daily shots.
S05	Photographing what they eat helps dieters stick to weight-loss plans and identifies bingeing.
S02	TORC gene linked to both appetite regulation and fertility
A29	Singh and Furberg editorialize against use of thiazolidinediones due to CV risk and lack of CV benefit.
A29	Pancreatic exocrine cells reprogrammed to make them into insulin-secreting beta cells
A27	Debate flares: Can obese patients be healthy?
A26	More cases of fatal pancreatitis after Byetta reported.
A26	Leptin injections keep rats with type 1 diabetes alive without insulin.
A20	New survey shows obesity rates continue to increase in the United States.
A19	Low-level arsenic exposure linked to increased type 2 diabetes risk.
A19	Obesity epidemic due to increased food intake, and not decreased activity level.
A19	FDA warns of hemorrhagic necrotizing pancreatitis with Byetta (exenatide)
A07	Bile acids play a role in glucose metabolism and insulin signaling.
A06	Broccoli compounds reduce reactive oxygen species induced in blood vessels by hyperglycemia.
A01	Consensus statement suggests that HbA1c is the best test to detect early diabetes.
J31	Two new drugs have profound effects on exercise conditioning in mice.
J29	New study highlights risk of losing bone density while following a low-calorie diet for weight loss.
J29	Testosterone changes associated with perimenopausal increase in metabolic syndrome risk.
J24	Complement activation is increases in patients with age-related macular degeneration.
J24	In acute study, fructose increases lipogenesis relative to glucose.
J17	U.S. population keeps getting fatter; esp. Alabama, Mississippi, and Tennessee.
J17	Whole fruits and fruit juices have opposite effects on diabetes risk in Nurses' Health Study
J14	Sodium phenyl butyrate (PBA) may prolong life of pancreatic beta cells in type 2 diabetes.
J08	Overweight patients trying to lose weight lose twice as much if they keep a food diary.
J03	FDA panel recommends that all new diabetes drugs be screened for cardiovascular risk.
J01	Doxycycline-inhibitable protease activity increased in SHR rats; this also may explain various aspects of metabolic syndrome.
J26	Fructose, but not glucose, increases visceral adipose tissue and triglycerides, and lower insulin sensitivity.
J25	Obesity drug rimonabant approved for NHS use in England and Wales.
J18	HHV-8 herpes virus linked to ketosis-prone type 2 diabetes in Africa.
J17	Big breakfast diet more effective than low-carb diet in maintaining weight loss.
J17	Diabetes doubles the risk of hearing loss.
J16	Studies with fat cells suggest that resveratrol may help combat obesity.
J11	FDA: Concern about potential cancer risk in users of Regranex (becaplermin) gel (used to help heal foot ulcers in diabetics).
J10	Rosiglitazone may slow progression of diabetic eye disease.
J10	Large Australian RCT specifically shows that lowering HbA1C in diabetics to a 6.5% target protects the kidney.
J10	NEJM: Full text of ADVANCE trial, which showed a benefit of intensive glucose control (HbA1C to 6.5%)
J09	NEJM: Glycemic control in the ADVANCE vs. ACCORD trials (editorial)
J09	NEJM: ACCORD trial results published (full text): Intensive blood glucose lowering in diabetes may worsen outcomes.
J09	VA diabetes trial reports at ADA. Lowering HbA1c below 7% associated with a trend for improved CV outcomes.
J09	Search abstracts being presented at the 2008 American Diabetes Association meeting.
J06	Why the two diabetes trials of aggressively lowering HbA1c came up with different results.
J05	NEJM: Aliskiren plus losartan lowers proteinuria in diabetics.
J03	USC researchers identify gene that controls blood glucose levels.
M29	Diabetes Tech and Therapeutics journal supplement focuses on self-monitoring of blood glucose.
M29	New microsphere-based vaccine for type 1 diabetes to be tested in humans. It reverses diabetes in mice.
M28	ADA Scientific Sessions start June 6th. Search abstracts at this link.
M28	Roche diabetes drug based on GLP-1 analogue, lowers HbA1c and engenders weight loss.
M28	Study suggests that salsalate may be of benefit in type 2 diabetics.
M27	High-flavonoid cocoa can be a boost for diabetics.
M27	Should HbA1c be used instead of plasma glucose to screen for diabetes?
M26	Qualitative changs in gut microflora affect insulin resistance.
M26	Six vs. three meals per day has no impact on weight loss.
M21	Genetic researchers identify numerous genes involved in synthesis and storage of fat in cells.
M21	Modest red wine (but not beer) ingestion actually may lower risk of NAFLD - non-alcoholic fatty liver disease.
M06	PNAS: Erythropoietin promoter polymorphisms associated with diabetic retinopathy and progression to ESRD.
M05	ASN Renal Week abstract archives 2003-2006 now available on-line in .pdf format.
M05	FDA Study: Injuries and deaths linked to insulin pump use in teens.
M04	Study suggests that the number of fat cells is set for life at adolescence, without change during dieting or weight gain.
M04	Nature genetics: More obesity genes found
M01	Obesity linked to heart failure and inflammatory mediator elevation in observational study.
A30	Ranibizumab better than laser photocoagulation for diabetic macular edema.
A29	JCEM study shows that trifusal, a salicylate-like drug, increases insulin secretion in obese non-diabetics.
A29	Thiazolidinediones (glitazones) may increase fracture risk in diabetics.
A23	Some compounds in Chinese bitter melon identified with activity against diabetes.
A23	High adiponectin levels linked to kidney dysfunction and albuminuria.
A22	New nanoparticle-based hydrogel allows orally administered insulin to be absorbed.
A21	New book emphasizes potential harm of high-fructose sweeteners.
A15	Vitamin D supplementation effective in relieving neuropathic pain in type 2 diabetes.
A12	Alginate-coated pancreatic beta cells from fetal pigs transplanted into 4 diabetics with mixed results.
A09	JAMA RCT shows American Indian tye 2 diabetics with LDL lowered to 70 have lower carotid IMT and LV mass than those with LDL lowered to 100.
A04	BCG vaccine reverses type 1 diabetes in mice; now a clinical trial is underway.
M31	More good data about pioglitazone suggesting reduction of atherosclerosis.
M31	Six new genetic variants associated with type 2 diabetes.
M28	Normal weight (BMI) obesity linked to metabolic syndrome.
M27	Keryx ends development of sulodexide after negative trial results.
M26	Chinese folk remedy vegetable, bitter melon, contains compounds that activate AMPK, similar to metformin.
M20	Insulin affects lifespan of C. elegans via inhibition of SKN-1.
M17	Dynamis Therapeutics announces discovery of new class of RAGE inhibitors.
M16	Blood vessel protein Robo4 reverses diabetic and age-related macular degeneration in mouse model.
M14	MGH study will determine if BCG vaccination halts type 1 diabetes in humans as it does in mice.
M12	Vitamin D supplements given to children may cut risk of subsequent development of type 1 diabetes.
M12	Keryx diabetes drug sulodexide fails to achieve primary endpoint in phase III clinical trial.
M11	Eli Lilly follows Pfizer and NovoNordisk in discontinuing inhalable insulin.
M10	Low levels of PYY, a food-induced gut hormone, may be an early marker for type 2 diabetes.
M06	7th Annual Prevention in Renal Disease Conference, Toronto, Sept. 19-20, 2008.
M05	A mystery: why does gastric bypass improve type 2 diabetes even without weight loss?
M04	Activating PPAR-delta suppresses inflammation in vascular tissues.
M04	PPAR-gamma knockout mice show hypertension and severe vascular dysfunction.
M04	Retinopathy may begin at lower blood glucose levels than expected.
F27	Addition of alpha-1-antitrypsin to 3-drug cocktail cures type 1 diabetes in mouse model.
F26	Heart attack rates fall in France following institution of national smoking ban in public places.
F26	FDA: Medication guide must be given to patients with each rosiglitazone (Avandia) prescription.
F21	Insulin-secreting beta cells created from stem cells.
F20	HbA1c test falsely low in dialysis patients due to short RBC survival; glycated albumin better reflects glucose exposure.
F14	International study of tight glucose control shows no evidence of increased death risk - contradicts US study
F13	University of Groningen study (PREVEND) emphasizes utility of treating hypertension in proteiniuric patients.
F13	UK's National Health Service approves pancreatic islet cell transplants for type 1 DM.
F08	Poor hyperglycemia control downregulates expression of fat-burning gene (diacylglycerol kinase delta)
F07	Identical twins study shows that obesity and waist size is 77% due to genetic factors.
F06	More on the halted NHLBI diabetes trial arm. Role of rosiglitazone use in the intensive treatment arm unclear.
F06	NHBLI stops intensive glucose lowering treatment arm of study due to excessive deaths.
F05	Type 2 muscle fibers, such as those increased by body building, improve metabolic syndrome in an animal model.
J31	Sweetened soft drinks and fruit juices linked to increased risk of gout in men.
J30	Breast size linked to diabetes risk
J28	24-h glucose monitoring suggests that coffee (via caffeine) ingestion worsens glucose control
J28	Blood levels of organochlorine pesticides linked to type 2 diabetes.
J25	Stem cells found in the pancreas.
J23	Obesity surgery found to be more effective than diet in curing type 2 diabetes.
J11	Sorbitol in sugar-free foods and gum, when ingested in high amounts, may cause diarrhea and weight loss.
J11	Lancet meta-analysis suggests that all diabetics should be on statins.
J09	Cannabinoid receptor blocking drug effective in causing weight loss.
J01	Lack of deep sleep may increase type 2 diabetes risk.
D28	American Diabetes Association comes out in support of lower carbohydrate diets.
D27	Bayer recalls certain lots of blood glucose test strips due to overly high readings.
D25	Higher levels of HDL in diabetes may inhibit NO via myristic acid binding - outcome effects unknown.
D25	Prevalence of diabetes in Dubai reaches 25%.
D19	Northwestern University gets 700 M royalties for diabetes pain drug patent.
D14	January JASN paper reports that PROActive (pioglitazone) associated with lower CV mortality in diabetics.
D12	More heart risks identified for Avandia.
D11	Physicians unaware of guidelines to treat patients with CV risk factors and metabolic syndrome.
D04	Waistline growth on high-carb diets linked to liver gene.
D04	Renin-angiotensin linked to obesity and insulin-resistance in a gene knockout animal model.
D03	Rosiglitazone stimulates osteoclasts, which may account for associtation with increased fracture risk.
D03	Low carb diet more effective than low fat diet in reducing inflammatory markers in patients with metabolic syndrome.
N26	High-glycemic intake carb intake linked to type 2 diabetes in African American and Chinese women.
N14	FDA adds black box warning of heart attacks for Avandia (rosiglitazone)
N14	Diabetics risk serious foot problems by wearing the wrong size shoes.
N06	Lancet: Fenofibrate treatment lowers risk for laser treatment in diabetic retinopathy.
N06	Mouse model demonstrates that inflammation, and not obesity per se, causes insulin resistance.
N06	New feedback pathway from fat cells to the pancreas to increase insulin secretion identified.
O29	Maggots to treat diabetic foot ulcers infected with MRSA.
O25	Charcot foot disease becoming more common as diabetic numbers increase.
O23	Early results with implantation of pig pancreatic islet cells to treat diabetes are encouraging.
O23	Global extent of obesity epidemic in the news.
O23	Direct link to FDA Byetta (exenatide) pancreatitis alert
O23	Acute pancreatitis associated with exenatide (Byetta) - FDA requires labeling change
O22	Chewing gum shown to help curb appetite and reduce cravings.
O12	Is fructose really that bad?
O08	New antibiotic ceftobiprole very effective in curing diabetic foot infections.
O01	Monitoring methyl nitrate levels in exhaled air may replace blood glucose testing in type 1 diabetics.
S24	All previous vitamin E trials fatally flawed due to underdosing.
S21	Huge rise in number of mothers with gestational diabetes.
S20	Thiazide diuretics exacerbate fructose-induced metabolic syndrome.
S10	Blocking Formation Of Toxic Plaques Implicated In Type 2 Diabetes
A30	New mechanism of action of thiazolidinediones discovered.
A27	Obesity rates climb in most states.
A27	Tiny retinal implants may allow the blind to recognize objects.
A23	Very high levels of reactive carbonyl compounds found in high fructose corn syrup.
A23	High fat mass secreting adiponectin can protect against metabolic syndrome in genetically engineered mice.
A21	Gustducin - new sugar-sensing receptor identified in the intestine; activated by artificial sweeteners
A18	Low carbohydrate diets and metabolism: Atkins may not have been so far off, after all.
A17	New roles for sirtuin 2 identified in controlling fat cell metabolism.
A10	New research shows skeleton to be an endocrine organ via osteocalcin.
A08	Annals: New study questions the increased heart attack risk with Avandia; original NEJM meta-analysis claimed to have been flawed.
A07	Masked thiamine deficiency (problems with RBC transketolase assay) linked to diabetic vascular disease.
J31	FDA panel recommends continued sale of Avandia, despite some evidence of increased heart risk.
J30	FDA Advisory Panel to explore safety and risks of Avandia.
J25	Obesity spreads among friends, study concludes.
J24	Soft drinks, including diet soft drinks, linked to 50% higher risk of metabolic syndrome.
J21	New Cochrane analysis focuses on increased side effects in patients taking rosiglitazone (Avandia)
J19	Weight loss pill rimonabant associated with increased suicide risk.
J17	Eating a high glycemic index diet is associated with age-related macular degeneration.
J16	Gene discovered that increases risk for type 1 diabetes in children.
J16	Older, cheaper pills just fine to treat diabetes.
J12	Hydroxychloroquine (Plaquenil) may be protective against developing type 2 diabetes.
J12	Serum levels of retinol-binding programs indicate level of visceral fat.
J10	Selenium supplements appear to raise risk of developing diabetes in RCT.
J26	Higher fat mass associated with less coronary artery calcification in type 1 diabetics.
J19	Randomization complete for phase III trial of sulodexide for diabetic nephropathy.
J19	Intentionally skipping insulin doses to lose weight - diabulimia - has severe consequences.
J07	New compound similar to aMSH, causing satiety, may be effective in controlling weight in the obese.
M25	NEJM: Full text of meta-analysis that found an increased risk of myocardial infarction with rosiglitazone.
M24	Oxychlorine-containing water - new treatment for diabetic foot ulcer infections.
M14	Effect of polyphenols (from apples, onions, green tea) on fat catabolism.
M14	Study shows unsuspected immunomodulatory effects of glucosamine.
M03	Maggots rid diabetic foot ulcer patients of MRSA
M03	Honey paste to treat diabetic foot ulcers
A30	Activating PPAR-delta may burn fat and reduce metabolic syndrome risk.
A27	New Genetic Risk Factors For Type 2 Diabetes Identified
A24	AGEs and food preparation may play an important role in chronic disease.
A18	Animal study suggests that changing to a low-fat diet can induce stress.
A16	Thrifty gene hypothesis of diabetes causation under dispute - no ethnic linkage found.
A14	Fish pollutants possibly linked to type 2 diabetes.
A12	Rebuilt immune system helps patients shake off diabetes
A05	Think that eating only once a day will make you lose weight? Nope.
A05	Reperfusion with glucose responsible for brain damage after hypoglycemic coma.
M30	Microencapsulated pig islet cells surviving and producing insulin in one patient ten years after implantation.
M26	DPP-4 inhibitor Januvia (sitagliptin1) approved for treatment of type 2 DM in Europe
M16	Fructose linked to deranged liver metabolism in rats, involving PPARs, leptin, and metabolic syndrome.
M16	Phthalate exposure linked to metabolic syndrome
M05	New type 1 diabetes susceptibility gene discovered.
F21	Apolipoprotein C1 linked to obesity and type 2 diabetes in American Indians.
F12	Type 2 diabetes genes mapped out
F07	Pine bark extract shown to be a potent inhibitor of GI glucose absorption
J29	Carbonic anhydrase-I linked to blood vessel leakage in diabetic retinopathy
J17	New class of insulin sensitizing compounds discovered for treating diabetes.
J15	Pancreatic-polypeptide containing chewing gum - a new potential weapon against obesity
J09	Carnosinase 1gene linked to progression to kidney failure in diabetics.
D26	Study identifies liver glucose sensor involved in regulation of endogenous glucose production
D20	Friendly microbes could make you fat: Bacteroides vs. Firmicutes
D19	Australians develop modified sugar product with low glycemic index.
D16	FDA updates labeling for Trasylol (aprotinin) regarding risk of renal dysfunction, anaphylaxis, and re-exposure.
D15	New theory of type 1 diabetes: Pancreatic sensory nerve damage and substance P - and you can prevent it in animals!
D15	VEGF blocker ranibuzumab shows impressive results in diabetic macular edema.
D15	Cytohesins may play a key, previously unrecognized, role in diabetes.
D12	Diet resulting in 10% body weight loss leads to measurable loss in bone density over 1-year period.
D11	FDA proposes rules overhaul to expand access to experimental drugs.
D05	Type 2 diabetes mellitus increasing markedly in children.
D04	Rosiglitazone vs. metformin or glyburide study: Is the benefit worth the disadavantages?
D04	Focus on exercise rather than diet helps guard obese patients against further weight gain.
D04	Rosiglitazone more effective than metformin or glyburide as monotherapy for type 2 DM.
N30	Overfeeding of pets leading to obesity and diabetes.
N27	Gene linked to wet form of macular degeneration.
N26	HDCN: Search index updated for audiofiles, slide/audio talks, articles, and abstracts
N23	New data suggests spleen cells can reverse type 1 diabetes in mice.
N20	Gut parasites in dragonflies cause "metabolic syndrome".
N13	Pioglitazone reduces progression of atherosclerosis in diabetics
N10	Asia on brink of diabetes disaster, experts warn.
N10	New technique can block VEGF inside cells, with implications for retinal neovascularization, cancer.
N09	Exercise and cutting calories each lower risk of diabetes to a similar extent.
N08	ACE2 enzyme may hold key to treatment of diabetic kidney disease.
N08	Chloroquine may improve metabolic syndrome.
N07	Retinal MRI poised to advance diagnosis of many types of retinopathy
N07	Why do we eat mindlessly and what would induce us to stop?
N06	Children's belly fat increases by more than 65% since 1990.
O31	Device measures skin fluorescence to determine amount of accumulated AGE burden in diabetics.
O25	FDA expands alert on counterfeit glucose test strips
O23	Diabetes susceptibility gene has important impact on whether or not type 2 DM will develop.
O19	Risk-benefit advantages questioned for pioglitazone in Cochrane systematic literature review.
O17	FDA approves new treatment for diabetets - Januvia (sitagliptin)
O12	Get on scale daily to keep off lost pounds.
O12	Higher magnesium intake lowers type 2 diabetes risk in African American women
O04	Pine tree bark extract improves functional measures of diabetic microangiopathy.
O02	High magnesium diet (in people without kidney disease) linked to lower risk of diabetes
O02	Mild vitamin C deficiency inhibits fat oxidation during submaximal exercise; may contribute to obesity.
S28	NEJM: Islet cell transplantation paper
S28	Pancreatic islet cell transplant in diabetes works - sort of (NEJM paper)
S26	Generex develops metformin-containing chewing gum, oral insulin spray, as novel drug-release products.
S20	Does vitamin D protect the kidney against diabetes?
S19	Poor quality of sleep linked to poor glucose control in type 2 diabetics.
S17	Glutamic acid decarboxylase (GAD) vaccine may prevent type 1 diabetes
S14	MMWR documents rising tide of obesity in the United States.
S14	Australian team discovers structure of insulin receptor.
S14	Pioglitazone shows benefits in terms of cardiovascular outcomes.
S12	Pancreatic primordia cells from pigs reverse type 1 or type 2 diabetes in rats
S11	Want to fight fat? Eat brown seaweed!
S05	U. Colorado researches identify gene that markedly increases risk of type 1 diabetes
S04	Obesity pandemic is sweeping the world
A21	Some diabetologists changing views of lower-carb diets for type 2 diabetes control.
A18	Role of BMI as a measure of obesity and cardiovascular risk questioned.
A09	Chronically high blood sugar linked to risk of cognitive impairment
A03	Is saturated fat evil? Think again. CLAs in dairy act similar to PPAR agonists; may be of benefit in diabetes
J28	Medi-honey helps heal problem wounds
J03	Study suggests infectious cause of type 1 diabetes
J01	Netrins grow nerves in diabetic mice.
J20	Type 2 diabetes rate doubles in last 30 years.
J20	Molecular mechanisms of vaccine against type 1 diabetes is revealed.
J16	CARI (Australasian) Clinical Practice Guidelines published (53 free full text review papers!)
J14	Hyperglycemia in non-diabetic ICU patients predictive of mortality, esp. in cardiovascular disease
J14	Low carb diet improves glycemic control in diabetes (pdf)
J14	Low carb diet reverses progressive renal disease in diabetic (case report)
J14	Feeding monkeys a high trans-fat diet markedly adds to abdominal fat.
J14	Serum levels of retinol-binding-protein-4 reliably predict insulin resistance.
J12	Ruboxistaurin helps protect vision in diabetics with nonproliferative retinopathy
J08	GCN5 protein key to regulation of glucose release by liver cells.
J01	For PD patients with diabetes: It's the carbs, stu...
M15	Antiviral gene variant linked to type 1 diabetes - consistent with viral causation theory.
M09	New triglyceride lipase enzyme found; its regulation may be key to some types of obesity
M07	Study suggests that aspartame does not raise risk of cancer
M07	Gene affecting angiogenesis around pancreatic beta cells linked to type 2 diabetes
M03	Mayo: 20 g sodium, 50% saturated fat diet improves BP, lipids in obese.
A28	Magnesium deficiency and metabolic syndrome re-emphasized
A27	Consuming a high glycemic index diet increases risk of age-related macular degeneration.
A25	University of Michigan to pay for preventive diabetes meds for its employees.
A24	Drug combination reverses type 1 diabetes in an animal model.
A19	American Association of Clinical Endocrinologists Annual Meeting abstracts (.pdf)
A04	Pine nut oil or conjugated linoleic acid both significant appetite suppressors.
M28	Juvenile diabetes reversed in animal model using dendritic cell injections.
M28	High-fat diet induces type 2 diabetes changes in mice via glut-2
M26	Restricting carbohydrates to 20-30% of dietary intake normalized blood glucose in type 2 DM
M19	AGE in blood vessels activates angiotensin II via RAGE-induced chymase
M16	Glycemic index is bupkus.
M12	Chromium of no benefit in type 2 diabetics
M10	Tight glucose control results in 50% lower incidence of neuropathy 10 years later in juvenile diabetics.
M08	Diabetes drug Byetta (exenatide) gaining attention as weight loss aid.
M07	Serum marker of artery damage linked so small increases in the BMI or waist-hip ratio.
M07	ADA releases tools for optimal management of diabetes in the Latino population.
M02	Hyperglycemia and hypoglycemia associated with use of gatifloxacin.
F27	Marijuana compound may help stop diabetic retinopathy
F26	Childhood obesity time bomb explodes.
F21	Alginate-encapsulated pancreatic islet cell transplants for diabetes.
F19	Pig islet cell transplants reverse diabetes in monkeys.
F10	IU scientists using stem cells to treat severe peripheral arterial disease.
J30	Certain adenovirus infections linked to obesity on animals and humans
J28	FDA approves first ever inhaled insulin for the treatment of diabetes.
J21	British study shows that work stress linked to both heart disease and metabolic syndrome.
J16	Strong linkage between one particular gene and type 2 diabetes confirmed.
J16	Canadian study suggests higher mortality among diabetics treated with sulfonylurea drugs vs. metformin.
J09	Is Alzheimer's disease a new form of diabetes, limited to the brain? Brown Medical School researchers say so.
J06	Post-marketing data detects new onset / worsening of macular edema in patients taking Avandia (rosiglitazone).
J02	UCSF study in Annals suggests that obesity increases risk of kidney failure.
J02	U.S. weighs obesity surgery options
D30	Ten most important findings relating to diet, health and lifestyle for 2005: Year in Review
D26	Diabetes, CHF home patient monitors taking off in the UK.
D25	Strict regimen reduces diabetes risk
D07	Fructose may be cause of obesity epidemic; also raises uric acid.
N29	Why trying to make couch potatoes exercise may be difficult.
N29	Fatty liver being seen increasingly in obese patients.
N28	High-carb diet linked to diabetic hypertension.
N17	Oralyn, an oral insulin-like drug, to be launched this month in Ecuador.
N17	Tea, cinnamon, buckwheat, and cherries for diabetics.
N16	Pioglitazone reduces heart attack rate in type 2 diabetics by 28%.
N13	Is type 2 diabetes a mitochondrial deficiency syndrome?
N13	ASN: Sulodexide phase 2 trial shows good results in diabetic nephropathy.
N07	NASA develops Star Trek glasses for the visually impaired.
N07	Millions of U.S. adolescents on the road to diabetes.
N07	Chlamydia found in 50% of eyes with wet form of macular degeneration.
N07	Taste bud receptor for fat identified in rat tongue.
N06	New FDA-supported website lists latest approved drug labels for all meds.
N05	MMWR: Progression in diabetics stabilizing or slowing in recent years.
N01	Diabetic blacks have less coronary artery disease than diabetic whites.
O30	CDC report estimates 7% of US population has diabetes.
O28	FDA delays decision on approving inhalable insulin
O27	New endogenous carbohydrate (INS2) discovered that lowers blood glucose.
O26	ASN Renal Week 2005 abstracts now available on-line.
O23	JAMA: Increased mortality after bariatric surgery.
O23	JAMA: Article detailing CV risk increase with Pargluva (muraglitazar)
O21	FDA approvable status for diabetes drug Pargluva raises safety concerns.
O12	China ranked 2nd in world incidence of diabetes.
O12	JAMA: ESRD incidence, prognosis improving in diabetics.
O12	Vanadium supplements speed recovery from infections (in mice).
O09	JASN: Glycosylated Hb in non-diabetic CKD pts. increases mortality risk.
O07	Lancet: Pioglitazone lowers risk of heart attacks and strokes in diabetics.
O07	Pegaptanib shows promising results in treating exudative macular degeneration.
O04	90% of Framingham cohort over 60 years of age now overweight.
S26	Smoking appears to double the risk of developing type 2 diabetes.
S20	Type 2 diabetes prevalent in Canada; many complications and poor control.
S13	New IDF global guideline for type 2 diabetes.
S13	Pioglitzaone improves cardiovascular outcomes in diabetics.
S13	High blood sugar levels linked to heart disease, even in nondiabetics.
S11	FDA approves first glitizar-class drug for treatment of type 2 diabetes.
S09	FDA advisory panel recommends approval of inhaled insulin.
S09	Spironolactone added to ACEI/ARB gives added renoprotection in diabetics.
S09	Reduction of severe hypoglycemic episodes another benefit of islet cell tx.
S09	Liver TORC2 identified as key regulators of blood glucose levels.
S06	Soy protein-rich diet may help prevent fatty liver of diabetes.
A28	Bluetooth mobile phone link allows diabetics to monitor trends in their glucose.
A26	Klotho gene may increase longevity by causing insulin resistance.
A26	Metabolic syndrome doesn't exist, diabetes groups claim.
A26	Metabolic advantage of protein-rich diets may be due to leucine.
A24	NEJM: EPO associated with proliferative retinopathy in patients and mice.
A24	TFAH releases report on obesity in America - we're all getting fatter.
A19	Magnetic nanoparticle MRI used to visualize inflammed pancreas in type 1 DM.
A19	New treatment may help prevent diabetic nerve damage and complications.
A18	Will FDA approve diabetes-related health claims for chromium picolinate?
A16	Low energy production in muscle mitochondria presages type 2 diabetes by 20 yrs.
A16	After overeating we don't compensate by eating less.
A16	PLEKHA1 gene linked to age-related macular degeneration.
A13	New type 2 diabetes gene discovered.
A13	NEJM: Retinoid X receptors - new targets to treat metabolic syndrome.
J26	NY diabetes patient tracking system raises privacy concerns.
J26	New gene therapy-based approach to diabetic neuropathy.
J22	Retinol-binding protein implicated in obesity, insulin resistance.
J22	NEJM: Statins had no effect on hard outcomes in diabetic ESRD patients.
J19	Double diabetes rising incidence in kids puzzles doctors.
J17	Faulty ENPP1 gene linked to diabetes and obesity.
J15	Ruboxistaurin reduces vision loss in diabetics with macular edema.
J13	New diabetes treatment to come from lizards.
J11	Patient navigator law to help low-income pts. with chronic disease, esp. DM.
J08	Ruboxistaurin lowers proteinuria in diabetic GN by 24%.
J07	Phase 3 trial begins of endothelin A receptor antagonist in diabetic nephropathy
J06	Coffee drinking may lower type 2 diabetes risk in adults
J30	ALLHAT subanalysis shows diuretics lower CV risk in diabetics as well as ACEI
J29	Keryx initiates phase 4 study of sulodexide to treat diabetic nephropathy.
J26	Gene hunters flock to Amish country.
J22	NEJM: CD3 antibody preserves residual beta cell fxn. in early type 1 diabetes.
J17	Study sheds light on why diabetes drugs (thiazolidinediones) cause edema.
J16	Tight control in diabetics markedly lowers later cardiovascular risk.
J13	American Diabetes Association Scientific Sessions - abstract search
J13	Incidence of diabetes in U.S. ESRD patients falls by 30%
J04	CDC defends its position about obesity and increased mortality risk.
M18	ASH: New onset diabetes 23% higher with amlodipine vs. valsartan.
M18	Is diabetes a result of survival advantage during the ice age?
M18	Modified liver cells keep diabetes under control.
M16	GP40 pancreatic beta cell receptors link high-fat diet to type 2 diabetes.
M10	Minocycline markedly reduces damage from diabetic-type retinopathy in rats.
M09	Pioglitazone reduces carotid artery thickness in diabetics.
M06	Pegaptanib shows promising results in treating diabetic macular edema.
M03	Schelling paper that is the basis for the dipstick protein-SC calculator
M03	Schelling-Case Western dipstick proteinuria/specific gravity calculator.
M02	FGF-21 finds itself as a new therapy for type 2 diabetes.
A29	FDA approves exenatide (Byetta) for adjunctive treatment of type 2 diabetes.
A27	Indirect evidence that NSAIDS may prevent age-related macular degeneration.
A27	Louisiana, Mississippi, Tennessee top 3 states in terms of CKD risk.
A26	Pyruvate may prevent brain damage after hypoglycemia in diabetics.
A20	Inhaled insulin to be available within a year in the EU.
A04	Human white blood cells can be induced to make insulin.
A02	Subintimal angioplasty offers new hope for peripheral vascular disease pts.
M22	Genes that increase susceptibility to type 1 diabetes mellitus identified.
M17	FDA approves Symlin to help manage diabetes.
M11	MMWR: Hepatitis B spread by fingerstick glucose testing in some nursing homes.
M10	Type 3 diabetes linked to low brain insulin, Alzheimer disease.
F25	Poor prenatal nutrition damages pancreatic beta cells
F22	Probably trigger of diabetic kidney disease uncovered (CD36)
F06	Living-related pancreatic islet cell transplant a success.
J18	U.S. launches diabetes campaign aimed at seniors.
J14	American Diabetes Association launches DOC News
J11	Does ingestion of cow's milk lead to diabetes? New study intends to find out.
J09	Lyrica (pregabalin) seems to work for diabetic pain, improves sleep.
J07	Periodontal disease predicts mortality in diabetic Pima Indians
D31	Fast food intake linked to obesity, insulin resistance.
D30	Heart failure patients treated with insulin have increased mortality
D28	NIH, JDRF, CDC announce new genetic data bank for diabetic kidney disease.
D22	Aspirin underused by people with diabetes.
D21	Chemicals found in cherries could help lower blood sugar in diabetics.
D14	Thiamine supplementation lowers CV risk in diabetics.
D13	Can a vaccine stop and cure type 1 diabetes? Trial to start soon.
D05	Risk of obesity-related deaths in the U.S may have been overstated.
N29	Testosterone deficiency found in 1/3 of diabetic men
N01	Rosiglitazone enhances fat cell energy metabolism
O29	New theory links low NAD/NADH ratio to diabetic organ damage
O26	KDIGO.org website now up for international kidney disease guidelines
O26	Gene therapy reverses diabetic neuropathy in mice
O26	Gene found that associates with insulin resistance, particularly in Hispanics
O19	CD36 gene polymorphisms tied to heart disease in diabetics
O18	Kaiser Permanente adult diabetes management guidelines
O16	MMWR: Focus on health disparities, diabetes in Hispanics (.pdf)
S20	Researchers target type 1 diabetes prevention
S08	FDA approves Cymbalta for management of diabetic neuropathic pain
A25	Diabetes now Mexico's leading cause of death
A24	Sugary soft drinks and fruit punches linked to diabetes in Nurses Health Study
A19	Paper studies clinical clues to cerebral edemia in diabetic ketoacidosis
A15	U.S. Latinos have high rates of eye disease and visual impairment
J23	SUMO-4 gene linked to type 1 diabetes
J16	High prevalence of diabetes in Hispanics in the news
J13	Governments drafting laws, policies, to tackle obesity
J12	SUMO-4 immunoregulatory gene linked to type 1 diabetes
J02	Lidocaine patch helps with diabetes pain
J28	Measuring blood sugar with a wave of the arm
J18	American Diabetes Assoc 2004 meeting - abstracts on-line
J18	Endocrine Society 2004 Annual Meeting - abstracts on-line
J12	Liraglutide once daily improves type 2 DM without weight gain
J09	American Diabetes Association Annual Meeting daily newspapers (pdf)
J07	Type 1 diabetes halted in mice with dendritic cell-assisted therapy
J06	Drug derived from gila monster saliva for type 2 diabetes
M31	Diabetes conundrum: Can control be too tight?
A14	Cinnamon may help to alleviate diabetes
M31	Compound shows promise in preventing type 1 diabetes
M09	Coffee cuts diabetes risk by up to 80% in Finns
F23	Islet cell infusion with anti-CD3 monoclonal Ab "cures" type 1 diabetes
F04	Gene therapy technique could aid islet cell transplant in diabetes
J27	Statins, ACE-inhibitors, improve outcomes in patients after leg bypass surgery
J20	Lisofylline prevents diabetes recurrence after islet cell transplant in mice
J12	Overweight Hispanic youth face increased risk of diabetes, metabolic syndrome
J02	LCM virus infection prevents type 1 diabetes in mice
D11	MSH may be involved in obesity - diabetes link
D09	US government CME pilot targets diabetes management
D07	MMWR: Diabetes among Hispanics in Los Angeles County
N29	Keryx announces sulodexide open access research collaboration with U. Mich.
N23	Steroid-sparing immunosuppression for solitary islet transplantation
N23	Cinnamon improves glucose and lipids in patients with type 2 diabetes
N21	Can GLP-1 heal ailing pancreatic beta cells?
N17	Macugen may help slow "wet" form of macular degeneration
N15	ASN: Kidney disease in African Americans, diabetes, linked to two chromosomes
N15	Spleen cells may develop into pancreatic islet cells in adult animals
N12	CREB acts through PPAR to regulate fat storage by the liver.
N03	GAD-2 gene linked to both obesity and type 1 diabetes mellitus
O24	Inhibition of insulin pathways in worms increases longevity to 500-worm years
O16	Altered TUG tethering of GLUT4 transporter a factor in insulin resistance
O02	PARP enzyme linked to blood vessel damage in diabetes
O02	Gastric bypass surgery can improve or cure type 2 DM in the very obese
S30	Icelanders find that one gene that makes you fat or thin
S15	New devices for glucose monitoring on the horizon
S09	Thiazolidinediones linked to heart failure in CKD diabetic patients
S08	Amgen and Biovitrum to develop novel anti-diabetic compounds
S02	Mouse, stripped of SCD-1 gene, resists both obesity and diabetes
A28	Chromium picolinate ups insulin sensitivity, and now we know how
A25	Lizard (Gila monster) spit a source of new type 2 diabetes drug
J31	Lengthening Achilles tendon reduces recurrence of diabetic foot ulcers
J28	Type 2 diabetes linked to a family of metabolic genes
J18	New class of diabetes drugs acts via glucokinase
J09	FDA approves dose-calculating insulin pump
J04	Gum disease increases death risk in diabetics
J03	ADA consensus statement: Dyslipidemia management in children and adolescents
J25	Kidney disease, retinopathy, common in type 2 DM in NHANES sample
J22	Am Diabetes Association (ADA) 2003 Scientific Sessions abstracts online
J19	Step counter helps diabetics increase their activity level
J17	VEGF injections stop neovascularization in a mouse model of retinopathy
J14	Vaccine slows progress of type 1 diabetes
J14	CDC issues diabetes warning for U.S. children: 1/3 will become diabetic
J05	NEJM: Intense diabetes therapy cuts heart, kidney trouble
M29	Drug related to D-xylose reduces blood glucose in diabetics via glucose uptake
M19	Potential new benefits for statins
M16	Does reduced mitochondrial activity underlie insulin resistance?
M12	AGEs in foods; do they play a role in uremia?
M02	BMJ: ABC of diabetes: The diabetic foot
A30	Rapid growth of diabetes prevalence among California Hispanics
A30	CTLA4 gene linked to type 1 diabetes and Graves disease
A30	Lisofylline shows promise in preventing type 1 diabetes
A22	Gene therapy cures diabetes in mice
A15	Ominous rise of adult diabetes in kids
A10	Blood flow and location of diabetic foot ulcers
A01	Diabetic women benefit from eating fish
M28	Promising results for islet cell transplantation may lead to cure
M26	Nanosensor may yield improved blood glucose sensor
F21	NIH launches ACCORD study; interventions designed to lower CV risk
F21	Increased death risk in diabetic women taking hormone replacement therapy
F17	Thiamine derivative prevents diabetic-related eye disease in rats
F13	Stanford U. helps patients with CHF, type 2 DM cope via web-info and support
J16	ADA 2003 diabetes clinical practice recs in full text
N20	Senate passes bill doubling funding for juvenile diabetes research
N09	Pandemic of diabetes among latinos gaining media attention
N07	Does coffee drinking protect against diabetes?
N04	American Diabetes Association Launches Latino outreach program
S09	Diabetes among Hispanics at record levels
A26	Xenical can delay onset of type 2 diabetes