TUFTS UNIVERSITY SCHOOL OF MEDICINE
"Redefining Chronic Renal Insufficiency:
A Panel Discussion on the Emerging Role of Anemia"
Post-Test Questions
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  1. The U.S. Pre-ESRD population (serum creatinine > 1.5 mg/dL) comprises approximately how many persons?
    2.
    1. 600,000
    2. 2,000,000
    3. 6,000,000
    4. 11,000,000

  2. Which of the following choices regarding prevalence by echo of LVH is correct?

    3. GP = general population, CRI = chronic renal insufficiency, HD/PD = dialysis, TX = transplant patients
    1. GP =10%, CRI = 20%, HD/PD = 40%, TX = 30%
    2. GP = 20%, CRI = 25-50%, HD/PD = 75%, TX = 50%
    3. GP = 10%, CRI = 20%, HD/PD = 75%, TX = 50%
    4. GP = 20%, CRI = 25-50%, HD/PD = 90%, TX = 70%

  3. What percent of CRI patients currently receive EPO?
    4.
    1. 10%
    2. 23%
    3. 48%
    4. 75%

  4. In the Canadian Multicentre Study, as CRI patients were followed over time, predictors of left ventricular growth were:
    5.
    1. increase in systolic blood pressure
    2. fall in hemoglobin
    3. baseline left ventricular mass index
    4. all three of the above

  5. Increasing the hematocrit from 24 to 36% improves cognitive function and there is a further improvement with full correction in some studies.
    6.
    1. True
    2. False

  6. Increasing hematocrit in the SLEEPO study from 32% to 42% had little effect on indices that measure quality of sleep and periodic limb movements during sleep.
    7.
    1. True
    2. False

  7. Whereas partial correction of the heamtocrit has marked effects on indices of quality of life such as the Sickness Impact Profile (SIP), there is no effect when hematocrit is increased above levels of 31%.
    8.
    1. True
    2. False

  8. According to the Greater Boston Area Chart Audit, whereas anemia management by generalists was suboptimal, as evidenced by use of EPO in only 30% of CRI patients with Hct values < 28%, once they were referred to nephrologists, EPO was used by nephrologists in almost all anemic CRI patients
    9.
    1. True
    2. False

  9. Which of these statements are true?
    1. Cardiovascular disease (CVD) starts early in CRI and has a high prevalence
    2. Cardiovascular disease (CVD) is a predictor of death
    3. Anemia during CRI is associated with an increased risk of CVD
    4. All three of the above

  10. In the USRDS data (Obrador et al), at onset of renal replacement therapy, what is the mean hematocrit level?
    11.
    1. 15%
    2. 21%
    3. 28%
    4. 36%