Ayala C, Reyna R, Steinberger E
Direct relationship between systolic blood pressure and serum
testosterone levels in a cohort of women with menstrual
dysfunction
11th Scientific Meeting, American Society of Hypertension
Am J Hypert
(Apr) 9:116A 1996
To determine the relationship between testosterone (T) and systolic
BP in women with menstrual dysfunction, 198 otherwise healthy, normotensive
women, age 18-46 had BP measurements along with determination of early
follicular phase T and dehyroepiandrosterone- sulfate. T was elevated in
55.5% of the cohort and was the strongest predictor of increased systolic BP
(>125 mm Hg). BP was also correlated with age and body mass index. Serum T
was also correlated with BMI, anovulation, and diastolic BP.
Comment: In this normotensive population with menstrual dysfunction,
serum T
appeared related to BP and BMI. The mechanism whereby T might alter BP,
whether this same correlation would hold in other populations, and how such
data should be applied clinically remains for future study.
Jason G. Umans, M.D., University of Chicago
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11th Scientific Meeting, American Society of Hypertension
H: Special problems :
Women
H: Special problems :
Endocrine hypertension