11th Scientific Meeting, American Society of Hypertension --Apr: 1996

Selected Abstracts




Hypertension


Calcium

h Modulation of resistance artery force generation by activation of an extracellular calcium receptor in the perivascular nerve network

Genetics

h Birth weight and adult hypertension and diabetes mellitus in US men

Vascular pathology

h Effect of KCl on central aortic pressure in elderly patients on beta-blocking drugs
h Vascular compliance in essential hypertension: Relevance of computerized arterial pulse waveform analysis

Kidney in hypertension

h Enalapril/HCTZ 20/6 mg reduces albuminuria in patients with essential hypertension: an atenolol controlled 3 month study
h Similar effects of 3 months treatment with losartan and enalapril on albuminuria, blood glucose, and lipids in patients with essential hypertension
h Angiotensin II and renal hemodynamic changes during mental stress in mild essential hypertension

Salt (sodium, chloride) sensitivity

h Increased endothelin-1 levels in human salt-sensitive hypertension

Sleep, sleep apnea

h Sleep apnea and sympathetic function

Sympathetic nervous system

h Muscle sympathetic nerve activity response to chronic felodipine therapy
h Sympathetic overactivity in pregnancy induced hypertension
h Mild renal insufficiency increases sympathetic nerve activity in humans

Ambulatory monitoring

h Impact of ambulatory blood pressure on left atrial size in uncomplicated hypertension
h Home blood pressure during pregnancy: establishment of standards of normalcy
h Demographic variables associated with diurnal blood pressure variations in essential and white coat hypertensives
h Home blood pressure measurements: relationship with clinic and blood pressure monitoring

Arm cuff

h Sitting with legs crossed raises blood pressure in patients with essential hypertension

White coat hypertension

h Spontaneous evolution of white coat hypertension

Role of exercise

h Left ventricular hypertrophy (LVH) in normotensives with exaggerated blood pressure response to exercise. Comparison between men and women

Outcomes

h Does microalbuminuria predict cardiovascular mortality in treated hypertensive men?

Endocrine hypertension

h Evidence for a bufodienolide Na/K pump inhibitor in human urine
h Routine determination of TSH for the detection of hypo- and hyperthyroidism in hypertensive women referring to a specialized centre
h Renal potassium excretion is normal in glucocorticoid remediable aldosteronism
h Effect of large doses of anabolic steroids on the diurnal blood pressure profile
h Renin and aldosterone measurements after captopril and supine position in differential diagnosis of adenoma and hyperplasia in primary aldosteronism
h The prevalence of primary aldosteronism using the response of plasma aldosterone/renin ratio to captopril as initial screening test in hypertensives
h The prevalence of primary aldosteronism in a hypertension continuing care clinic

Ethnic populations

h Increased incidence of angioedema in blacks treated with ace- inhibitors
h Hypertension in American Indians: The Strong Heart Study
h Heritability of salt sensitivity in African American families
h Dysregulation of renal kallikrein responses to mineralocorticoid secretagogues in African Americans

Pheochromocytoma

h Frequency of pheochromocytoma in adrenal incidentalomas and utility of glucagon test for the diagnosis
h The importance of converting enzyme inhibition in pheochromocytoma study

Women

h Direct relationship between systolic blood pressure and serum testosterone levels in a cohort of women with menstrual dysfunction
h Clinic and ambulatory BPs show different patterns and relationships in males and females
h Angiotensin converting enzyme inhibitor fetopathy
h Estrogen supplementation attenuates vasoconstrictor responses to norepinephrine and decreases total body norepinephrine spillover in perimenopausal women

ACE inhibitors

h ACE inhibitors given at night give better control of early morning blood pressure
h Sexual activity in hypertensive males treated with lisinopril or atenolol: a cross-over study
h Regression of structural alterations in small subcutaneous resistance arteries after long-term antihypertensive treatment with lisinopril in hypertensive patients with LVH
h Racial similarity in response to the angiotensin converting enzyme inhibitor trandolapril

Alpha and alpha/beta blockers

h Doxazosin for the treatment of patients with hypertension and symptoms of benign prostatic hyperplasia

Calcium channel blockers

h Effects of long term antihypertensive therapy on left ventricular remodeling: the treatment of mild hypertension study
h Subcutaneous tissue pressure as a method to evaluate the oedematiginos potential of amlodipine versus verapamil

Compliance

h Influence of socioeconomic factors in maintaining enrollment in a tertiary hypertension clinic

Diuretics

h Results of treatment of hypertension with beta-blocker:diuretic combinations -- focus on a very low-dose approach
h Antihypertensive efficacy and tolerability of a low-dose reserpine/thiazide combination compared to an ace-inhibitor in first-line treatment

Chronotherapeutics

h Scant effect of antihypertensive monotherapy on nocturnal blood pressure in patients with obstructive sleep apnea

Dietary/electrolyte therapy

h Replacing regular salt with a sodium-reduced, potassium- and magnesium- enriched mineral salt may offer a non-pharmacological approach to lowering blood pressure
h Homocysteine and renal disease


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