Schmieder RE, Gatska CK, Langenfeld MRW, Schobel HP, Veelken
R
Angiotensin II and renal hemodynamic changes during mental
stress in mild essential hypertension
11th Scientific Meeting, American Society of Hypertension
Am J Hypert
(Apr) 9:43A 1996
Patients with essential hypertension typically have altered renal
blood flow, but the etiology is uncertain. Both the sympathetic
nervous system and renin angiotensin system probably are involved.
Renal hemodynamics were determined at rest and during sympathetic
mental stress in 45 normotensives and 37 essential
hypertensives. Glomerular filtration rate (GFR) and renal
plasma flow (RPF) were similar in both groups at rest. However,
mental stress resulted in a more marked increase in GFR and
angiotensin II in hypertensives than in normotensives (p < 0.001).
This hyperfiltration was inhibited by the ACE inhibitor cilazapril.
(David J. Leehey, M.D., Loyola University at Chicago)
To go back use the BACK button on your browser.
Otherwise click on the desired link to this article below:
11th Scientific Meeting, American Society of Hypertension
H: Pathophysiology :
Kidney in hypertension
H: Drug therapy :
ACE inhibitors