Bohlender J, Menard J, Wagner J, Luft F, Ganten D
Human renin-dependent hypertension in rats made transgenic for
human angiotensinogen
16th Scientific Meeting of the International Society of Hypertension
ISH Abstract Book
(Jun) 16: 1996
Rats transgenic for human angiotensinogen - specific for human renin -
became hypertensive when infused with human renin. This shows that
increased angiotensinogen can increase blood pressure and provides a
useful experimental model for human renin-dependent hypertension
(Alan Jardine, M.D., Glasgow University, Scotland).
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16th Scientific Meeting of the International Society of Hypertension
H: Pathophysiology :
Genetics