Selected Abstracts
This review was prepared by Dr. Carmine Zoccali (Reggio Calabira, Italy) and Dr. Alan Jardine
(Glasgow, Scotland). Dr. Carmine Zoccali acted as coordinator. Additional reviews were supplied by
Dr. Richard Dart (Marshfield, WI, USA).
Hypertension
Heart in hypertension
h 
Increased expression of TGF-beta isoforms by human monocytes of
hypertensive patients
Endothelium, Nitric Oxide
h
Urinary nitrate in humans: does it correlate with high blood pressure?
Fetal origins, birth weight
h
Fetal origins of hypertension
h
Vascular network geometry: the missing link between birth
weight and cardiovascular risk?
Genetics
h
Human renin-dependent hypertension in rats made transgenic for human
angiotensinogen
h
ACE insertion/deletion polymorphism is associated with carotid
artery intima-media thickness, but not left ventricular mass, in a
general population
h
General comments on genetic association studies in hypertension
h
Associaion analysis of microsatellite polymorphism for nitric oxide
synthase gene in hypertensives
h
Abnormal microvascular structure in subjects with familial
predisposition to high blood pressure
h
A genetic variant of methylene-tetrahydro-folate reductase (MTHFR)
and risk of parental myocardial infarction
h
Two putative functional variants of the ACE gene locus involved in the
genetic determination of plasma ACE
h
The insertion deletion polymorphism of the human ACE gene
differentiates the response to enalaprilat in normotensive males
h
Human hypertension caused by a single point mutation in the type 2 11-beta
-hydroxysteroid dehydrogenase (h11 b-HSD2) gene
h
An angiotensin-II type 1 microsatellite allele is associated with
lower blood pressure
h
Renin angiotensin system genetic variants and pressure load in
cardiac hypertrophy
Vascular pathology
h
Programmed cell death in vascular disease and hypertension
Kidney in hypertension
h
Vitamin C induced recovery of the renal vasodilatory response to l-
arginine in essential hypertension
h
Counter-regulation of renal responses to L-arginine in hypertensive
patients with renal insufficiency
h
Does renal function influence the response to antihypertensive
agents? Results from the HOT study
Salt (sodium, chloride) sensitivity
h
Endothelial dysfunction in human salt-sensitive hypertension
h
Uroguanylin: Circulating natriuretic peptide from the intestinal
mucosa and heart
h
Long-term effecs of neonatal sodium restriction on blood pressure
h
Salt depletion impairs insulin sensitivity in NIDDM
Sleep, sleep apnea
h
Sleep and blood pressure: Baroreflex sensitivity in dippers and non-
dippers
Arm cuff
h
Prediction of blood pressure trends in borderline hypertension
Role of exercise
h
Four weeks of cycling augments forearm vasoconstrictor response to
L-NMMA
Endocrine hypertension
h
Production of adrenomedullin in human vascular endothelial
cells
h
Plasma proadrenomedullin N-terminal 20 peptide in patients with
hypertension and renal failure
h
Different plasma corticosteroid patterns in normotensive and
hypertensive subjects
Hypercalciuria
h
Blood pressure and bone density are inversely related in the
elderly
Renovascular hypertension
h
Renal artery stent placement slows progression of renovascular
hypertension
Smoking, ethanol, substance abuse
h
A prospective study of coffee intake and hypertension: The Johns
Hopkins Precursors Study
ACE inhibitors
h
Neutral endopeptidase inhibitors cause vasoconstriction in man
Calcium channel blockers
h
Long-term study of calcium antagonists: Reassessment of the Furberg
hypothesis
Dietary/electrolyte therapy
h
Inverse relationship between dietary protein markers and blood
pressure -- findings for 10,020 men and women in Intersalt
Dialysis, Chronic Renal Failure
Complications (acute)
d
Vasodepressor syncope in haemodialysis patients
Cardiovascular/Hypertension
d
Endogenous nitric oxide production in patients with chronic renal
failure
Progression
d
Ambulatory diastolic blood pressure lower than 80 mm Hg postpones
decline in renal function in patients with chronic renal disease
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