Buoncristiani U, Fagugli R, Pinciaroli MR, Kulurianu H, Bova C
Better control of anemia by daily hemodialysis
XVIth Annual CAPD Conference
Perit Dial Int Suppl 2 (Feb) 16:S99 1996

Buoncristiani's "daily" home HD regimen, unlike that of Dr. Uldall (see Pierratos et al) is to treat for 1.5-2 hours daily 6-7 times per week. He presented data on 34 patients switched from conventional HD to daily HD, focusing on changes in hematocrit and EPO dose. The mean hematocrit increased from 25 to 30%, despite the fact that EPO dose was reduced in 8 of the patients, some times (in 4 patients) to zero.

Comment: This data is in accord with that recently published in NEJM by Eli Friedman's group in which Hct improved with increasing Kt/V. There is the possibility of a small confounder with daily home hemodialysis: because interdialytic weight gain is less, one would expect less hemodilution and therefore a higher Hct in the predialysis blood samples; however, a 5 point increase in Hct is greater than would be expected from changes in hemodilution alone. (John T. Daugirdas, M.D., Univ of Illinois at Chicago)

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XVIth Annual CAPD Conference
Basic hemodialysis : Home hemodialysis
CRF by problem area : Anemia/Erythropoietin/Iron