Chandler CL, Valentini RP, Bunchman TE
Protocol for intraperitoneal erythropoietin
XVIth Annual CAPD Conference
Perit Dial Int Suppl 2
(Feb) 16:S66 1996
Chandler et al used erythropoietin, 300 units/kg/week given
intra-peritoneally in 25 ml of normal saline (followed by a 20 ml
flush) after cycler treatment in children. The erythropoietin was
allowed to dwell for 4 hours, after which a midday exchange was
performed (without draining the erythropoietin). The hematocrit
remained stable and peritonitis incidence was not increased.
Comment: Intra-peritoneal erythropoietin administration has
previously been described by Bargman et al (PDI 1992;12:369-372) and
Ateshkadi et al (Am J Kidney Dis 1993;21:635-642). IP administration
is most effective if given into a "dry" abdomen with a prolonged
dwell. This is a feasible mode of administration in patients, such
as children, who are afraid of needles.
(Beth M. Piraino, M.D., University of Pittsburg)
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XVIth Annual CAPD Conference
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