Cueto-Manzano AM, Espinosa A, Hernandez A, Correa-Rotter R
Peritoneal transport rates do not correlate with nutritional
status in Mexican CAPD patients
XVIth Annual CAPD Conference
Perit Dial Int Suppl 2
(Feb) 16:S5 1996
The authors evaluated the extent to which peritoneal transport
rate (PTR) correlates with nutritional status (NS). They selected 42
patients who had been peritonitis-free for at least 6 weeks. D/P was
evaluated during a PET test. They also performed a 24h dietary inquiry, a
nutritional scoring assessment, and then measured creatinine clearance
and weekly
urea Kt/V. Nine patients had normal nutritional indices, whereas 6 had mild,
9 moderate and 18
severe malnutrition. The only correlation observed with PTR, expressed as
D/P, was with the serum albumin level. No correlation was observed between
PTR and
nutritional satus.
The authors conclude that hypoalbuminemia present in high transporters may be
associated to
factors others than peritoneal losses or lower synthesis.
Comment: Contrary to reports by others, the authors
do not find correlation between PET results expressed by D/P and
nutritional status. These discordant results demonstrate that large
studies are necessary to
evaluate the impact of peritoneal transport on nutrition. Interpretation of
all
such studies may be complicated by the occurrence of peritonitis. For
example,
we have no data here on the
number of peritonitis episodes and their duration. Peritonitis may
induce either
severe hyperpermeability or severe hypopermeability, both associated with
low nutritional status. In addition, dietary assessment in this study
was based on a single day history, which is too short: three days of dietary
intake should be assessed at least, and 7 days would be recommended.
(Christian Verger, M.D.,
Pointoise, France)
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XVIth Annual CAPD Conference
Basic peritoneal dialysis :
PET testing
CRF by organ system :
Nutrition