Smith L, Folden T, Youngblood B, Panlillio F, Gotch F
Clinical evaluation of a peritoneal dialysis kinetic modeling
set
XVIth Annual CAPD Conference
Perit Dial Int Suppl 2
(Feb) 16:S13 1996
The authors decribe a special "kinetic modeling" quick disconnect set which
is fabricated with a small "T" off the drain line at the bag inlet. This "T"
permits collection of a representative aliquot of spent dialysate from each
bag during a kinetic
modeling day. Results using dialysate samples obtained from this
connector were compared with results where all bag contents were pooled and
an
aliquot of the mixture was used to determine BUN, creatinine, and glucose
concentrations.
Similar daily urea and creatinine clearances were obtained with
the two methods of dialyate sampling. However, the new method allows for
calculation of mass transfer coefficient, as the solute concentrations of a
timed
dwell are also known.
Comment: This method seems quite practical. However it
relies on the assumption that aliquots are all perfectly sampled
and analysed and that there is no error
in the weighing of each bag. In centers where people are less trained to
perform such protocols we are concerned about the fact that
mutliple single errors at each aliquot sampling might induce significant
error when extrapolating
to the 24 hour dialysate collection. This technique deserves to be
checked in practice in different centers. (Christian Verger, M.D.,
Pointoise, France)
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XVIth Annual CAPD Conference
Basic peritoneal dialysis :
Chronic PD regimens, adequacy, modeling
Basic peritoneal dialysis :
PD solutions, equipment