Detection of parvovirus B19 DNA in renal biopsies of patients with idiopathic collapsing glomerulopathy
ASN 30th Annual Meeting, San Antonio
J Am Soc Nephrol (Sep) 8:94A 1997
The authors report an interesting association between parvovirus and idiopathic collapsing glomerulopathy. using PCR they noted that they could detect the presence of the virus in the kidneys of 9 of 10 patients with the collapsing lesion but only rarely in idiopathic focal segmental glomerulosclerosis and normal controls. The authors suspect that the virus could be related to the pathogenesis of the collapsiong lesion. Additional data including screening of the samples of patients with other renal lesions, and animal experiments with the virus are needed to evaluate the possibilty of the association being etilologic, i.e., Koch's postulates need to be fulfilled. (B.S. Kasinath, M.D., University of Texas at San Antonio)
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ASN 30th Annual Meeting, San Antonio
Proteinuria/Hematuria : Focal, collapsing GN
Proteinuria/Hematuria : Other systemic infections