Selected Abstracts
Hypertension
Preadolescent and adolescent
h 
Detection and prevalence of arterial hypertension in school age
children from Braganca Paulista, Sao Paolo, Brazil
Kidney in hypertension
h
Differences in glomerular membrane permeability responses to a non-
dihydropyridine (NDHP) and dihydropyridie (DHP) calcium channel
antagonist (CCA) in patients with diabetic nephropathy:
h
Outcome of scleroderma renal crisis (SRC).
h
Angiotensin II acts against both the afferent and efferent
arterioles via type IA receptor to the same extent, not with predominance
of the efferent arteriole--direct evidence using AT1a
h
Is microalbuminuria a predictor of cardiovascular and renal
events in essential hypertension (EH)?
h
Microalbuminuria (MA) is a marker for cardiovascular (CV) risk
in young adults.
Sympathetic nervous system
h
Evidence against elevated sympathetic activity in borderline
hypertension.
Renovascular hypertension
h
High grade renal artery atherosclerosis in patients with chronic renal
insufficiency is not characterized by a rapid (< 6 months) decline in
renal function
h
Beneficial effect of ace inhibition on survival of patients with
renovascular hypertension (RVH).
h
Intravascular stents in the treatment of renal artery stenosis
(RAS).
h
Detection of severe bilateral atherosclerotic renovascular disease by
ACE-inhibitor induced renal dysfunction.
ACE inhibitors
h
ACE I/D polymorphism and short-term renal response to ACE inhibition;
Role of sodium status
h
Safety of losartan in hypertensive patients with asymptomatic
hyperuricemia.
Chronotherapeutics
h
Age-race subgroup vs renin profile as predictors of blood
pressure response to antihypertensive therapy in 292 patients: Results
of the VA cooperative study.
h
Renin profile as a predictor of blood pressure response to
antihypertensive therapy in 1292 patients: Results of the VA cooperative
study.
Dialysis, Chronic Renal Failure
Vascular Access: graft/fistula
d
Silent infection in clotted hemodialysis access graft.
d
Management of cuffed tunned dialysis catheter infection.
d
A comparison between PTFE and denatured homologous vein (DVH) grafts
for hemodialysis access: A randomised multicenter trial.
d
Hemodialysis vascular access and surgical training.
d
The value of low intra-access pressure (IAP) in detecting and
excluding low access blood flow.
d
Clinical study of a hematocrit (H)-based method to determine vascular
access blood flow rates (QA) without saline injection (SI).
d
Brachytherapy in the prevention of re-stenosis after
percutaneous transluminal angioplasty (PTA) for central venous stenosis
(CVS).
(Intermittent) dialysis for ARF
d
Indication for dialysis influences outcome from acute renal
failure (ARF) the ICU; Results from a radomized multicenter trial.
d
Acute peritoneal access and high frequency peritoneal dialysis in
intensive care patients
d
Urea disequilibrium contributes to underdialysis in the intensive
care unit.
d
Dose of intermittent hemodialysis (IHD) and outcome of acute renal
failure (ART): A prospective randomized study.
Vascular Access: venous
d
Factors influencing function and survival of temporary hemodialysis
catheters.
Complications (acute)
d
pH of the washing solutions for dialysis filters and generation of
vasodilatory mediators (bradykinin and nitric oxide): Role in first use
syndrome
d
Midodrine as a treatment for intradialytic hypotension.
d
Plasma sodium (CpNa) "setpoint": Relationship to interdialytic weight
gain (IWG) and mean arterial pressure (MAP) in hemodialysis patients (HDP).
d
Neurologic symptoms and death associated with the use of cellulose
acetate dialyzers.
Adequacy, prescription, urea kinetics
d
Mortal risk and URR: Differences among demographic groups.
d
Sraightening out the J-shaped curve: The relation between dialysis dose and
mortality is dependent on total body water.
d
Effect of changes in dialytic frequency, duration and flow rates on
solute kinetics and effective clearances.
d
Effect of vascular access type and blood draw method on recirculation
and rebound in the HEMO study.
d
Dialysate side Kt/V -- a whole body approach
Reuse, theory and practice
d
Increases in membrane porosity after reuse with citric acid and
heat.
Cardiovascular/Hypertension
d
Falsely elevated troponin T but not troponin I in patients with renal
impairment
d
Renalism: Bias in the utilization of inpatient cardiac
catheterization (CATH) in patients with chronic renal
insufficiency (CRI).
d
Diagnosis of cardiac injury in renal disease patients: Value of
cardiac troponins.
d
Cardiac troponin I (CTI) is a reliable marker of acute myocardial
infarction (MI) in end stage renal disease (ESRD) patients.
d
Higher levels of antioxidant defenses in chronic renal patients in
hemodialysis treated with ACEi.
d
Acute effects of high dose furosemide on residual renal function in
CAPD patients.
Anemia/Erythropoietin/Iron
d
Frequent IV iron dosing is associated with higher infectious
deaths.
d
Hematocrit level is a predictive factor for future
hospitalization events.
d
Patient survival is associated with hematocrit (HCT) level.
d
Sodium ferric gluconate complex in sucrose: Safer than iron
dextran.
d
Subcutaneous (SC) versus intravenous (IV) administration of
recombinant human erythropoietin (rHuEPO) in hemodialysis (HD)
patients (pts).
d
Intravenous iron hydroxysaccharate: Establishing the optimum dose.
d
Efficacy of frequent dosing of iron dextran on epogen dose and cost on
a stable vs mixed maintenance hemodialysis (HD) population.
d
Parenteral iron causes increased lipid peroxidation in
hemodialysis patients.
Bone disease/aluminum
d
An open label, cross-over study of the new phosphate binder RenaGel in
the management of hyperphosphatemia in ESRD patients.
d
Suppression of parathormone by calcitriol therapy in hemodialysis
patients: A meta-analysis.
d
Downregulation of osteoblast PTH/PTHrP receptor mRMA expression in
renal failure.
d
Experimental evidence for strontium (Sr) to play a role in the
development of dialysis related osteomalacia (OM).
d
Pharmacokinetics and pharmacodynamics of pamidronate disodium in
hemodialysis.
d
Use of one-alpha-hydroxyvitamin D2 (1alpha D2) in 121 hemodialysis
patients with secondary hyperparathyroidism: A phase 3 trial.
d
19-Nor safely and effectively reduces PTH levels in hemodialysis
patients.
Drug use in CRF
d
Possible neurologic effects of fentanyl in dialysis patients
Infections (other than hepatitis, peritonitis)
d
Cefazolin for empiric treatment of HD-related infections:
Efficacy and blood concentrations.
d
Pharmacokinetics of quinupristin/dalfopristin (Syndercid RP 59500) in
patients receiving continuous ambulatory peritoneal dialysis (CAPD).
CRF in infants and children
d
Acquired cystic kidney disease (ACKD) in children undergoing
dialysis and with renal transplants
d
Intradialytic (ID) weight and ambulatory blood pressure (BPM)
correlate positively in children and adolescents receiving hemodialysis.
Nutrition
d
Zinc supplementation reduces plasma cortisol levels in zinc-
deficient patients with end-stage renal disease (ESRD)
d
Subjective global assessment (SGA) does not correlate with routine
biochemical markers in evaluating nutrition in hemodialysis (HD)
patients (PTS).
d
Effect of L-carnitine on protein catabolic rate (PCR) in
chronic hemodialysis patients (CHD).
d
Effect of oral supplementation on nutritional indices in
chronic hemodialysis patients.
d
Transferrin (TF) and serum prealbumin (PAlb) are early predictors of
albumin (Alb) in chronic hemodialysis patients (CHD).
d
High body mass index (BMI) does not adversely affect cardiovascular
(CV) and all-cause mortality in hemodialysis patients
d
Plasma carnitine as a marker of protein malnutrition.
d
Significant correlation between near-infrared interactance and
nutritional parameters in hemodialysis patients.
Outcomes (Morbidity, Mortality)
d
A multinational hemodialysis patient survival comparison.
d
Income is a very important independent variable that affects
survival of patients with ESRD.
Surgery in ESRD
d
Surgical mortality and morbidity in patients with end-stage renal
disease
PD solutions, equipment
d
Overestimation of blood glucose measurements by auto-analyser method
in CAPD patients (pts) treated with icodextrin.
Peritonitis and exit-site infection
d
Effect of lactate or bicarbonate buffered CAPD solutions on
netilmycin bactericidal activity/
Chronic PD regimens, adequacy, modeling
d
The importance of residual renal function for survival in
patients on peritoneal dialysis.
d
Admitted noncompliance [NC] with CAPD exchanges is more common in
US than Canadian patients.
d
A description of the delivery of peritoneal dialysis (PD) in the US.
Progression
d
End stage renal failure: Discrepancy between theoretical practice and
reality
d
The angiotensin-converting-enzyme (ACE) inhibitor ramipril slows the
rate of GFR decline and the progression to end stage renal failure
(ESRF) in proteinuric, non-diabetic chronic renal
Kidney in hypertension
d
Effect of various antihypertensive drugs on microalbuminuria and
progression of renal disease in essential hypertension (EH)
Clinical Nephrology
Cyclosporine, ARF in transplant patients
c
Cyclosporine (CsA)-induced nephrotoxicity (NT) in auto-immune diseases
(AID): A meta-analysis.
c
Bioequivalence comparison of Sandimmune and Neoral versus Sang-35
cyclosporine in kidney transplant recipients
Other drug-associated ARF
c
Amiodarone, a forgotten nephrotoxic?
Hemolytic/uremic syndrome and TTP
c
Familial hemolytic uremic syndrome (HUS).
c
Long-term prognosis of children with severe diarrhea-associated (D+)
hemolytic uremic syndrome (HUS): Comparison of patients in high
versus low incidence areas
Acute interstitial nephritis/NSAID
c
HIV protease inhibitor associated nephritis
Papillary necrosis
c
Fifteen year follow-up of reflux nephropathy (RN) by radiological
imaging
Hereditary polycystic disease
c
Phenotype PKD2 vs PKD1; results from the European concerted action.
c
Autosomal dominant polycystic kidney disease (ADPKD) in African
Americans: Prevalence and clinical course.
c
Polycystin expression in PKD-1, infantile PKD-1 and TSC-2/PKD-1 cystic
kidney: Evidence against a two-hit disease mechanism in cyst
initiation.
Creatinine clearance
c
Prediction of decline in GFR from estimated creatinine clearance in
chronic renal failure
Fanconi syndrome
c
Dent's like proximal renal tubular disorder in a First Nations'
kindred.
Hyponatremia
c
Indirect evidence to suggest that hyponatremia by itself cotributes to
the high urate clearance in the SIADH
c
Saline infusion is useful in most SIADH patients and the
increase in plasma sodium is related to urinary osmolality and not to urinary
sodium and potassium loss
Treatment (CEI, indomethacin, lipid drugs)
c
Does albumin enhance the diuretic action of furosemide in nephrotic
syndrome?
c
Efficacy and safety of recombinant human serum albumin in refractory edema
accompanying nephrotic syndrome
Metabolic acidosis
c
Fanconi's syndrome: an Acadian variant
c
Lactic acidosis induced by stavudine (d4T)
c
Autoantibody to carbonic anhydrase II may be responsible for
pathogenesis of renal tubular acidosis in Sjogren's syndrome
c
A heterozygous missense mutation in the AEI CT/HCO3 exchanger gene
cosegregates with autosomal dominant distal renal tubular acidosis
(dRTA) in two unrelated families.
c
Mutations in the chloride-bicarbonate exchanger gene AEI in autosomal
dominant but not autosomal recessive distal renal tubular acidosis.
Metabolic alkalosis
c
Renal tubular alkalosis with chronic hyperkalemia
Renal biopsy techniques, tips, complications
c
Outpatient percutaneous renal biopsy in high risk patients
c
The clinical efficacy of transjugular renal biopsy.
c
Slide platelet aggregation time (SPAT) does not correlate with
bleeding time (BT) in patients with renal failure undergoing biopsy.
Diagnostic approach to hematuria
c
The comparison of the urine RBC phase contrast microscopy and
immuoperoxidase stain in differentiation of renal and nonrenal
hematuria
c
Nut-cracker syndromes: As one cause of unknown origin
hematuria to nephrologists in spite of studies for hematuria
Diagnostic approach to proteinuria
c
Simplified screening for microalbuminuria
c
Proteinuria in atheroembolic disease
Cryoglobulinemia not due to hepatitis
c
A peculiar type of interstitial infiltrates in cryoglobulinemia
glomerulonephritis (CryoGN).
Diabetes
c
Predictors of microalbuminuria in individuals with insulin
dependent diabetes mellitus (DDM). An update
c
Threshold effect of hyperglycemia on the progression of
microalbuminuria in type I diabetes
c
Successful pancreas transplantation (PT) alone reverses established
lesions of diabetic nephropathy (D) in man
c
Preservation of normal GFR with long-term captopril treatment
in normotensive IDDM patients with microalbuminuria
c
Initial decrease in proteinuria after institution of ACE inhibitor
treatment predicts long term prognosis for kidney function in
overt diabetic nephropathy
c
Long-term follow up of the eight patients with diabetic nephropathy
who experienced remission of nephrotic syndrome during the
captopril study
c
Effects of pyridoxamine, a novel post-Amadori AGE inhibitor, on
nephropathy induced by glycated albumin.
Focal, collapsing GN
c
Therapy of FSGS with nephrotic syndrome--3 years follow up of a
prospective randomised multicenter study
c
Glomerular tip lesion (GLT): clinical features, response to
corticosteroids and comparison to focal segmental glomerulosclerosis (FSGS)
c
Detection of parvovirus B19 DNA in renal biopsies of patients with
idiopathic collapsing glomerulopathy
IgA Nephropathy
c
Long-term treatment with fish oil reduces renal progressionn in
patients with IgA nephropathy (IgAN)
c
Two year steroid therapy in progressive IgA nephropathy--A
prospective, controlled 10-year follow-up study
Hereditary hematuria/proteinuria
c
Outcome of renal transplantation in patients with Alport's
syndrome (AS).
Lupus nephritis
c
The prevalences and clinical characteristics of ANCAs in lupus
nephritis
c
Activity of lupus nephritis as related to serum levels of soluble
Fas
c
Mycophenolate mofetil therapy in patients with cyclophosphamide-(CyP)
resistant or relapsing diffuse proliferative lupus nephritis (SLE-
DPGN)
Vasculitis (Wegener's PAN, etc.)
c
Cyclosporine for the prevention of relapses in ANCA-associated
vasculitits
c
Mycophenolate mofetil is effective for maintenance therapy of
systemic vasculitis
Renal Stones: Diagnosis
c
Low gastrointestial absorption of alkali as a cause of idiopathic
hypocitraturia
Renal Stones: Etiology
c
Reduced bone mass in asymptomatic mothers and their children with
idiopathic hypercalciuria (IH).
c
Age-related variations in urine chemistry risk factors for kidney
stone formation.
Renal Stones: Treatment
c
Enalapril causes low urinary citrate excretion in normal human
volunteers.
c
Beverage use and the risk of kidney stones in women
c
Intake of vitamins B6 and C and risk of kidney stones in women
Transplantation
c
Reversal of adynamic bone disease after successful renal
transplantation.
c
Effect of oral potassium citrate on urinary excretion of
aluminum after renal transplantation.
c
Intermittent oral calcitriol and intravenous pamidronate in renal
allograft recipients: Divergent effects on bone metabolism and
parathyroid function.
c
A controlled, comparative study of two regimens (750 mg bid and 500 mg bid)
of oral ganciclovir in the prevention of cytomegalovirus
infection in post-kidney transplant "CMV at risk" rec
c
Renal thrombotic microangiopathy associated with anticardiolipin
antibodies in hepatitis C positive renal allograft recipients
c
Vascular and interstitial features of cellular renal allograft
rejection: Effects on therapy and outcome
c
The association of chronic kidney graft failure with recipient
blood pressure.
c
Should eosinophilia be included in the Banff classification of renal
allograft rejection?
c
Ganciclovir (G) pharmacokinetics in renal transplant patients (RTR)
with cytomegalovirus (CMV) infection.
c
Thymoglobulin reverses refractory acute rejection in kidney
transplant recipients.
c
Predictors for the recurrence of IgA disease following renal
transplantation.
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