A comparison between PTFE and denatured homologous vein (DVH) grafts for hemodialysis access: A randomised multicenter trial.
ASN 30th Annual Meeting, San Antonio
J Am Soc Nephrol (Sep) 8:153A 1997
It is known that graft survival rate is higher, and infection rate is lower, with an AV fistula vs. an AV graft, presumably due to the deleterious effects of foreign body associated with the latter but also because with an AV fistula, the returning blood stream does not have to cross an anastomosis with its resulting post-anastomotic turbulent area. Be that as it may, there is far less good data comparing the two principal graft materials: PTFE vs. homologous vein. The latter material is not very popular in the United States. In this study from The Netherlands, which was prospective and randomized, graft survival and infections were compared in 130 patients randomly assigned to be implanted with a PTFE or homologous vein (HV) graft.
Primary patency at 18 months was not different with the two graft materials, being 22 and 28%, respectively. Secondary patency rates and incidence of thrombosis also were comparable. The major difference found was the incidence of infection (9 HV vs. 20 PTFE grafts, p = 0.08), and associated surgical intervention rate. The conclusion of the study was, that HV grafts are associated with a lower infection rate than when PTFE is used. (John T. Daugirdas, M.D., University of Illinois at Chicago)
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ASN 30th Annual Meeting, San Antonio
Basic hemodialysis : Vascular Access: graft/fistula