Noh JW, Koh KS, Koo JR, Kim HJ, Kim KH, Chun RW, Chae DW
Nut-cracker syndromes: As one cause of unknown origin
hematuria to nephrologists in spite of studies for hematuria
ASN 30th Annual Meeting, San Antonio
J Am Soc Nephrol
(Sep) 8:95A 1997
The authors present 5 patients with episodic gross hematuria
attributed to the so-called "nutcracker syndrome", the compression of
the left renal v. between the SMA and the aorta. 3/5 had renal
biopsy, described as normal (but no comment if EM was done to rule
out thin basement membrane). The diagnostic gold standard used was
renal vein venography with manometry of left renal vein and v.cava: a
gradient of 3mmHg and presence of collateral veins are diagnostic.
Cystoscopy showed
unilateral blood flow in 4/4 cases. Venous phase renography during
angiography was not helpful. RBCs were not dysmorphic.
Comment: Surprisingly, authors did not use Doppler ultrasound, which
was reported to be diagnostic by another group in the same city
(Seoul, South Korea)
Radiology 198:93-97, 1996.
Proteinuria was not
mentioned, but has been described in nutcracker syndrome
Pediatric Nephrology 11:218-220, 1997.
This abstract is useful in reminding us
of this syndrome in the differential diagnosis of gross hematuria.
(James A. Sondheimer MD, Wayne State University, Detroit, MI)
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ASN 30th Annual Meeting, San Antonio
Proteinuria/Hematuria :
Diagnostic approach to hematuria