Noh JW, Koh KS, Koo JR, Kim HJ, Kim KH, Chun RW, Chae DW
Nut-cracker syndromes: As one cause of unknown origin hematuria to nephrologists in spite of studies for hematuria
ASN 30th Annual Meeting, San Antonio
J Am Soc Nephrol (Sep) 8:95A 1997

The authors present 5 patients with episodic gross hematuria attributed to the so-called "nutcracker syndrome", the compression of the left renal v. between the SMA and the aorta. 3/5 had renal biopsy, described as normal (but no comment if EM was done to rule out thin basement membrane). The diagnostic gold standard used was renal vein venography with manometry of left renal vein and v.cava: a gradient of 3mmHg and presence of collateral veins are diagnostic. Cystoscopy showed unilateral blood flow in 4/4 cases. Venous phase renography during angiography was not helpful. RBCs were not dysmorphic.

Comment: Surprisingly, authors did not use Doppler ultrasound, which was reported to be diagnostic by another group in the same city (Seoul, South Korea) Radiology 198:93-97, 1996.   Proteinuria was not mentioned, but has been described in nutcracker syndrome Pediatric Nephrology 11:218-220, 1997. This abstract is useful in reminding us of this syndrome in the differential diagnosis of gross hematuria. (James A. Sondheimer MD, Wayne State University, Detroit, MI)

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ASN 30th Annual Meeting, San Antonio
Proteinuria/Hematuria : Diagnostic approach to hematuria





The article on Nutcracker syndrome is interesting. Am anxious to read the full article if it accepted for publication. I suspect that the editors will want to know about lordosis and whether a change in posture affected the pressure differences. Also, the editors will want to know if the episodic nature of the hematuria was influenced by physical activity.
Vincent R. Pateras M.D. (v-pateras@nwu.edu)
Evanston, IL USA-Sunday, April 19, 1998 at 18:33:02 (PDT)