Neyra R, Shyr Y, Hakim RM, Ikizler TA
Transferrin (TF) and serum prealbumin (PAlb) are early predictors of albumin (Alb) in chronic hemodialysis patients (CHD).
ASN 30th Annual Meeting, San Antonio
J Am Soc Nephrol (Sep) 8:205A 1997

In this study, earlier markers of nutritional status were analyzed prospectively in a group of 105 chronic hemodialysis patients. Using restricted residual maximum likelihood based mixed effect models, the intra correlation between transferrin, prealbumin, and albumin were determined monthly for 16 consecutive months.

The analysis revealed that early changes in both transferrin and serum prealbumin significantly predicted changes in serum albumin levels. The predictive power decreased as the length of follow up increased. A regression equation was developed which demonstrated that a change of 0.1 g/dL in albumin can be predicted by change of 8 mg/dL in the same direction by either transferrin or serum prealbumin levels. It was felt that both transferrin and prealbumin were early and strong predictors of serum albumin levels and that they potentially may be used to identify patients at risk for developing protein calorie malnutrition. Michael V. Rocco, M.D., Bowman Gray School of Medicine

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ASN 30th Annual Meeting, San Antonio
CRF by organ system : Nutrition